Results 121 to 130 of about 514 (246)

Predictive Value of [−2]proPSA‐Related Indices for Prostate Cancer Detection Years Before Prostate‐Specific Antigen Elevation: Insights From a Five‐Year Longitudinal Screening Cohort

open access: yesThe Prostate, EarlyView.
ABSTRACT Background [‐2]proPSA(p2PSA)‐related indices have demonstrated diagnostic value for detecting prostate cancer (PC) in males with modest increases in prostate‐specific antigen levels (PSA) of < 10 ng/mL. However, the “leak point” of p2PSA level in the blood circulation before developing screen‐detectable PC remains uncertain.
Yoshitaka Sekine   +11 more
wiley   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux   +6 more
wiley   +1 more source

Scaling turbulence drives the general circulation

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
The NOAA Gulfstream SP4, which deployed the GPS dropsondes over the NE Pacific Ocean as part of the Winter Storms Project during the January–March periods of 2004, 2005 and 2006. Abstract Statistical multifractal analysis of airborne and dropsonde observations is used to show that persistence of velocity after molecular collisions breaks the continuous
Adrian F. Tuck
wiley   +1 more source

Impact of Weak‐Constraint Four‐Dimensional Variational data assimilation on the prediction of a sudden stratospheric warming event in 2024

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
The Weak‐Constraint Four‐Dimensional Variational (WC‐4DVAR) system markedly improved the analysis and forecasting of the 2024 sudden stratospheric warming (SSW) event. It reduced biases and enhanced 7–9 day predictions of temperature across the SSW life cycle, with the most pronounced gains for winds also during the critical onset period.
Shaoying Li   +5 more
wiley   +1 more source

Evaluation and assimilation of Arctic Weather Satellite data in the AROME‐Arctic forecast system

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
The Arctic Weather Satellite (AWS), launched in August 2024, is a prototype for the future EPS–Sterna constellation of small satellites carrying an innovative microwave sounder. We present the first assessment of AWS in the regional AROME‐Arctic numerical weather prediction system, covering post‐launch calibration results and the impact of AWS ...
Stéphanie Guedj   +2 more
wiley   +1 more source

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