Results 51 to 60 of about 12,206 (264)

Analysing biodiversity observation data collected in continuous time: Should we use discrete‐ or continuous‐time occupancy models?

Methods in Ecology and Evolution
Biodiversity monitoring is undergoing a revolution, with fauna observation data being increasingly gathered continuously over extended periods, through sensors like camera traps and acoustic recorders, or via opportunistic observations.
Léa Pautrel, Sylvain Moulherat, Olivier Gimenez, Marie‐Pierre Etienne   +3 more
doaj   +1 more source

Safeguarding Asian tapir habitat in Sumatra, Indonesia

Oryx
The Asian tapir Tapirus indicus is the only tapir species in Southeast Asia. It is declining across its range and is categorized as Endangered on the IUCN Red List.
Irene M.R. Pinondang, Nicolas J. Deere, Maria Voigt, Ardiantiono, Agus Subagyo, Alexander Moßbrucker, Antika Fardilla, Desy S. Chandradewi, Fahrudin Surahmat, Febri A. Widodo, Gabriella Fredriksson, Hariyo T. Wibisono, Jatna Supriatna, M. Irfansyah Lubis, Nuri Asmita, Sunarto, Tengku Lidra, Tomi Ariyanto, Wido R. Albert, Wilson Novarino, Wulan Pusparini, Yoan Dinata, Matthew J. Struebig   +22 more
doaj   +1 more source

Introduction to Occupant Modeling

, 2023
With the fundamental and design processes established, this chapter dives into occupant modeling theory and techniques. Following Chapter 2, it starts with basic concepts of occupant behavior and occupant actions. It provides some retrospective analysis of how occupants are currently modeled in design practice and building codes (based on several ...
O'brien W., Cali D., De Simone M., Tabadkani A., Azar E., Rajus V. S., Agee P., Schweiker M., Rysanek A.   +8 more
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Binturong ecology and conservation in pristine, fragmented and degraded tropical forests

Oryx
The persistence of seed-dispersing animals in degraded habitats could be critical for ensuring the long-term conservation value and restoration of forests.
Arata Honda, Zachary Amir, Calebe P. Mendes, Jonathan H. Moore, Matthew Scott Luskin   +4 more
doaj   +1 more source

Modelling species distribution from camera trap by‐catch using a scale‐optimized occupancy approach

Remote Sensing in Ecology and Conservation, 2021
Habitat selection is strongly scale‐dependent, and inferring the characteristic scale at which an organism responds to environmental variation is necessary to obtain reliable predictions.
Jolien Wevers, Natalie Beenaerts, Jim Casaer, Fridolin Zimmermann, Tom Artois, Julien Fattebert   +5 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Model predictive HVAC control with online occupancy model [PDF]

Energy and Buildings, 2014
This paper presents an occupancy-predicting control algorithm for heating, ventilation, and air conditioning (HVAC) systems in buildings. It incorporates the building's thermal properties, local weather predictions, and a self-tuning stochastic occupancy model to reduce energy consumption while maintaining occupant comfort.
Dobbs, Justin R., Hencey, Brandon M.
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Histone-Net: a multi-paradigm computational framework for histone occupancy and modification prediction

Complex & Intelligent Systems, 2022
Deep exploration of histone occupancy and covalent post-translational modifications (e.g., acetylation, methylation) is essential to decode gene expression regulation, chromosome packaging, DNA damage, and transcriptional activation.
Muhammad Nabeel Asim, Muhammad Ali Ibrahim, Muhammad Imran Malik, Imran Razzak, Andreas Dengel, Sheraz Ahmed   +5 more
doaj   +1 more source