Results 111 to 120 of about 109,798 (256)

Engineered 3D cultured human nasal mucosa mesenchymal stem cell derived sEVs for targeted brain‐derived neurotrophic factor delivery to enhance neurogenesis and attenuate brain damage

Interdisciplinary Medicine, EarlyView.
This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang, Junge Chen, Jiao Xia, Weitong Yang, Teng Ma, Tianzi Shan, Weifeng He, Gaoman Zhang, Zhuoran Xia, Weiwei Wang, Zhusheng Liu, Zhiqiang Yi, Piye Niu, Tian Chen   +13 more
wiley   +1 more source

Occupational Health of Staff Nurses Working in Private Hospitals during the Early Post-Pandemic Period of COVID-19

South East Asia Nursing Research
The COVID-19 pandemic has significantly impacted healthcare professionals, causing issues like anxiety, hopelessness, and difficulty sleeping. Occupational health encompasses nurses' physical, mental, emotional, and social well-being and has been ...
Edmar E Blancaflor, Ma. Ericka Jhanina L Cariaga, Jeselle Angelene B Coloma, Hainah S Pangcoga, Alfrey J Corpuz, Jonalyn P Santos   +5 more
doaj   +1 more source

Interpersonal Predictors of Youth Internalizing Symptom Trajectories During the COVID‐19 Pandemic

Journal of Adolescence, EarlyView.
ABSTRACT Introduction The COVID‐19 pandemic disrupted youths' interpersonal relationships, posing risks for internalizing distress. Yet, evidence remains limited beyond the early pandemic waves and with changing interpersonal contexts. This study examined trajectories of youth internalizing symptoms across five timepoints of the pandemic and ...
Nicole S. J. Dryburgh, Ryan Miller, Eric Duku, Katherine T. Cost, Yun‐Ju (Claire) Chen, Jordan Edwards, Emma Nolan, Katholiki Georgiades   +7 more
wiley   +1 more source

Reward Deficits in Co‐Occurring Social Anxiety and Depression: The Roles of Anhedonia, Boredom, Loneliness, and COVID‐19 Social Restriction

Journal of Clinical Psychology, EarlyView.
ABSTRACT Prior research points toward reward deficits as crucial to the link between social anxiety disorder and major depressive disorder. However, studies have not explored specific types of reward deficits or how social‐environmental factors may impact them. The current study examined whether the indirect effects of three reward deficits (anhedonia,
Nathan M. Hager, Alicia L. Milam, Hannah C. Hamrick, Benjamin Swanson, Matt R. Judah   +4 more
wiley   +1 more source

Young adult self‐harm: The role of victimisation and polygenic risk in a population‐based longitudinal study

JCPP Advances, EarlyView.
Abstract Background Victimisation has been associated with self‐harm (with or without suicidal intent), but little is known about this association during young adulthood—a distinct developmental period. Further, not all individuals who experience victimisation will later engage in self‐harm, suggesting the influence of other factors.
Filip Marzecki, Isabelle Ouellet‐Morin, Helena M. S. Zavos, Sylvana Côté, Richard E. Tremblay, Jean‐Philippe Gouin, Massimiliano Orri, Michel Boivin, Marie‐Claude Geoffroy   +8 more
wiley   +1 more source

Analysis of University Students' Mental Health from the Perspective of Occupational Harmony.

PLoS ONE
BackgroundMental health problems are common among university students. Based on the Model of Occupational Harmony, we investigated the relationship between occupational engagement and mental health among Chinese university students.MethodsA mixed methods
Yijun Liu, Ruiqi She, Jin Xing
doaj   +1 more source

Assessment Of Malpractice Fear and Occupational Anxiety Of Intern Doctors

Tıp Eğitimi Dünyası
Aim: The internship period is a critical period during which medical candidates experience increased clinical responsibilities and intense professional anxiety and fear of making mistakes. The increased professional responsibilities and concerns about the consequences of decisions made during internships can profoundly impact not only interns ...
Onur Er, Özge Arslangiray, Didem Arslantaş, Alaettin Ünsal   +3 more
openaire   +1 more source

Are sensory processing difficulties in infancy predictive of child mental health at 5‐years? Findings from the Etude Longitudinale Francaise depuis l'Enfance French national birth cohort

JCPP Advances, EarlyView.
Abstract Background People with neurodevelopmental and mental health conditions have been demonstrated to have elevated rates of sensory processing (SP) difficulties in research and practice but the temporal order of this relationship is unclear. Methods This study sought to investigate whether SP difficulties in infancy predicted mental health at 5 ...
Emma Butler, Michelle Spirtos, Mary Clarke   +2 more
wiley   +1 more source

Association between occupational balance and the physical and mental health of the university community: an observational study

Frontiers in Public Health
AimsThe study aims to explore the influence of occupational balance on the physical and mental health of working university students and to describe the existing correlations within the university community between sociodemographic variables and physical
Elisabet Huertas-Hoyas, Elisabet Huertas-Hoyas, Cristina García-Bravo, Cristina García-Bravo, Cristina García-Bravo, Jorge Pérez-Corrales, Jorge Pérez-Corrales, Elisa Bullón-Benito, Gemma Fernández-Gómez, Gemma Fernández-Gómez, Mª Pilar Rodríguez-Pérez, Mª Pilar Rodríguez-Pérez   +11 more
doaj   +1 more source

Evaluation and treatment of mental health symptoms among unaccompanied migrant children and adolescents in the United States: A systematic review

JCPP Advances, EarlyView.
Abstract Background Unaccompanied migrant youths are at elevated risk for exposure to trauma and related mental health challenges, but there is minimal evidence guiding best practices. We conducted a systematic review of quantitative studies that examined mental health evaluation and treatment services for unaccompanied migrant youths resettled in the ...
Natan J. Vega Potler, Sebastian Villegas, Dorice Vieira, Sarah M. Horwitz   +3 more
wiley   +1 more source