Results 151 to 160 of about 26,310 (273)

Establishment of a Human Cell‐Based In Vitro Test System for Investigating and Evaluating Cytotoxic and Immunomodulatory Effects of Indoor Mold

Environmental Toxicology, EarlyView.
ABSTRACT Mold growth in damp indoor environments is a widespread problem associated with respiratory health effects, though causal mechanisms remain incompletely understood. We established a human cell‐based in vitro test system using bronchial epithelial cells (NuLi‐1) and macrophages (THP‐1) to assess inhalation toxicity and immunomodulatory effects ...
Anja Wolff, Jessica Reinert, Silke Steinborn, Marion Berger, Judith Neuhoff, Lennart Marske, Kerttu Valtanen, Udo Jäckel, Stefanie Klar   +8 more
wiley   +1 more source

Worldwide Burden of Hearing Loss Across Childhood and Adolescence, 1990–2021, and Projection to 2050

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives This article aims to analyze the trends in hearing loss (HL) prevalence and years lived with disability (YLDs) in children and adolescents from 1990 to 2021, and the corresponding health inequalities, decomposing causes, and future trends.
Jiao Zhang, Da‐Yong Wang, Xiao‐Nan Wu, Jin Li, Chang‐Shuo Shan, Yu‐Di‐Yang Ma, Chun‐Yan Liu, Yao‐Hua Tian, Qiu‐Ju Wang   +8 more
wiley   +1 more source

Who Is a Patriotic Man? Rethinking Hegemonic Masculinity in Modern Iran

Gender &History, EarlyView.
ABSTRACT This article examines the analytical viability of the concept of “hegemonic masculinity” in the historical study of masculinities in early‐twentieth‐century Iran (c.1890–1941). It argues that a radical problematizing of the concepts of hegemony, class, “the West,” and patriotism helps us move beyond the binaries of Western‐Iranian and modern ...
Ali Hashemian
wiley   +1 more source

Integrating Social and Clinical Determinants of Pre‐Eclampsia: A Hierarchical Systematic Review and Conceptual Framework for Prevention

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Pre‐eclampsia is a leading cause of maternal and perinatal morbidity and mortality, with risk factors reported across a vast literature base fragmented between social and clinical factors. Objective To develop a comprehensive conceptual framework of the strongest risk factors and their relationships contributing to pre‐eclampsia ...
Mai Lei Woo Kinshella, Jeffrey N. Bone, Terteel Elawad, Hiten D. Mistry, Laney Poye, Eleni Tsigas, Deepika Devadas, Violet Mateljan, Marie‐Laure Volvert, Marianne Vidler, Hannah Blencowe, Véronique Filippi, Laura A. Magee, Peter von Dadelszen, The PRECISE Network, Umberto D’Alessandro, Anna Roca, Hawanatu Jah, Andrew Prentice, Melisa Martinez‐Alvarez, Brahima Diallo, Abdul Sesay, Sambou Suso, Baboucarr Njie, Fatima Touray, Yahaya Idris, Fatoumata Kongira, Modou F. S. Ndure, Lawrence Gibba, Abdoulie Bah, Yorro Bah, Marleen Temmerman, Angela Koech, Patricia Okiro, Geoffrey Omuse, Grace Mwashigadi, Mary Goretti Amondi, Consolata Juma, Joseph Mutunga, Moses Mukhanya, Robin Okello, Onesmus Wanje, Isaac Mwaniki, Marvin Ochieng, Emily Mwadime, Esperança Sevene, Corssino Tchavana, Salesio Macuacua, Anifa Vala, Helena Boene, Lazaro Quimice, Sonia Maculuve, Inacio Mandomando, Peter von Dadelszen, Laura A. Magee, Rachel Craik, Marie‐Laure Volvert, Hiten Mistry, Thomas Mendy, Donna Russell, Prestige Tatenda Makanga, Liberty Makacha, Reason Mlambo, Lucilla Poston, Rachel Tribe, Sophie Moore, Tatiana Salisbury, Aris Papageorghiou, Alison Noble, Rachel Craik, Hannah Blencowe, Veronique Filippi, Joy Lawn, Matt Silver, Joseph Akuze, Ursula Gazeley, Judith Cartwright, Guy Whitley, Sanjeev Krishna, Marianne Vidler, Jing (Larry) Li, Jeff Bone, Mai‐Lei (Maggie) Woo Kinshella, Domena Tu, Ash Sandhu, Kelly Pickerill, Carla Carillho, Benjamin Barratt   +87 more
wiley   +1 more source

Occupational mortality in older workers: A forensic autopsy‐based evaluation

Journal of Forensic Sciences, EarlyView.
Abstract The aging of the global workforce has led to an increasing number of individuals remaining occupationally active at older ages. However, forensic autopsy‐based data on workplace deaths in this population remain limited. This study aimed to evaluate the causes and manners of workplace‐related deaths among individuals aged 65 years and older ...
Muhammet Ali Oruç, Hüseyin Çağrı Şahin, Muhammed Oduncu, Muhammed Fatih Yaman, Abdulkadir Can   +4 more
wiley   +1 more source

Cautionary Tales for Science‐Based Policy in Deep‐Sea Mining Governance

Global Policy, EarlyView.
ABSTRACT This article examines how low‐certainty scientific claims permeate high‐stakes policy debates before rigorous validation. Using deep‐sea mining governance as a focal domain, the study traces high‐visibility narratives, including the “dark oxygen” hypothesis, radioactive risks of polymetallic nodules, projected impacts of sediment plume ...
Lucía Villar‐Muñoz
wiley   +1 more source

Beyond abstinence: Redefining success in cannabis use disorder treatment

Addiction, EarlyView.
Abstract Background Over two decades of pharmacotherapy research has yet to yield a consistently effective medication for cannabis use disorder (CUD), in part because clinical trials have frequently prioritized abstinence as a primary or key endpoint.
Tobias B. Atkin, Frances R. Levin, John Mariani, Christina A. Brezing   +3 more
wiley   +1 more source

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Allergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery, Rüçhan Ekren, Emilie Bérard, Aurélie Du‐Thanh, Hugo Rimet, Fatma Jendoubi, Vanina Lenief, Nadia Raison‐Peyron, Amel Bouznad, Maria P. Konstantinou, Jonathan Rioual, Lilian Basso, Juliette Mouiren, Manon Boussier, Brigitte Milpied, Cristina Bulai Livideanu, Louise Jaulent, Florence Hacard, Marine A. Lefevre, Audrey Nosbaum, Julien Seneschal, Marc Vocanson, Carle Paul, Nicolas Gaudenzio, Marie Tauber, on behalf of the French Atopic Dermatitis Network from de GREAT Research group   +25 more
wiley   +1 more source

Keratinocyte Priming by Staphylococcus aureus Reduces HSV‐1 Susceptibility

Allergy, EarlyView.
ADEH+ patients have a reduced microbial diversity with increased S. aureus and S. epidermidis colonization compared to ADEH− and healthy controls. Heat‐killed S. aureus reduced HSV‐1 susceptibility and release of infectious progeny virus in a keratinocyte in vitro model. Heat‐killed S.
Phila Cara Baumann, Rebecca Pospich, Katinka Döhner, Ilona Klug, Julio Cesar Villalvazo Guerrero, Jan Hartmann, Inken Harder, Wolfgang Lieb, Barbara Kind, Andreas Kleinheinz, Susanne Abraham, Matthias Augustin, Elke Weisshaar, Jochen Schmitt, Stephan Weidinger, Beate Sodeik, Thomas Werfel, Lennart M. Roesner, Stephan Traidl, The TREATgermany Study Group   +19 more
wiley   +1 more source

Parental Educational Attainment at Birth and Biomarkers of Male Fecundity: A Study From the Danish National Birth Cohort

Andrology, EarlyView.
ABSTRACT Background Low parental education is associated with poorer offspring health, but its influence on male fecundity remains unclear. Objective To study the association between parental educational attainment at birth and biomarkers of male fecundity in young men and to explore whether this association is mediated by maternal smoking in pregnancy
Anne Hjorth Thomsen, Anne Gaml‐Sørensen, Sandra Søgaard Tøttenborg, Onyebuchi A. Arah, Siri Eldevik Håberg, Mikko Myrskylä, Cecilia Høst Ramlau‐Hansen   +6 more
wiley   +1 more source