Results 201 to 210 of about 90,712,137 (281)

Climate change, environmental exposures, and breast cancer: advancing climate-resilient oncology through sustainable development goal 13. [PDF]

Front Public Health
Obeagu EI.
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Association of Life's Essential 8 Score With Incident Pancreatic Cancer: A Prospective Cohort Study in Shanghai, China

Cancer Science, EarlyView.
In this prospective cohort study of 60,556 cancer‐free adults with a median follow‐up of 7.44 years, a higher Life's Essential 8 (LE8) score, reflecting better cardiovascular health, was associated with a lower risk of pancreatic cancer (PC). Each 1‐SD increase in LE8 score was associated with an 18% lower PC risk.
Liping Yi, Xing Liu, Maryam Zaid, Kexin Zhang, Biying Wang, Yingqi Deng, Minhua Tang, Yonggen Jiang, Genming Zhao   +8 more
wiley   +1 more source

Perioperative Durvalumab for Resectable NSCLC: Updated Outcomes for Japanese Patients in AEGEAN

Cancer Science, EarlyView.
In prespecified exploratory analyses of Japanese patients with resectable NSCLC enrolled in the AEGEAN trial, perioperative durvalumab plus neoadjuvant chemotherapy demonstrated clinically meaningful improvements in the primary endpoints of EFS and pCR versus neoadjuvant chemotherapy alone.
Tetsuya Mitsudomi, John V. Heymach, Yoshitsugu Horio, Fumihiro Tanaka, Hiroshi Tanaka, Shoichi Kuyama, Morihito Okada, Shinichi Toyooka, Yasutaka Watanabe, Martin Reck, David Harpole, Janis M. Taube, Yuka Olivo, Huiling Xiong, Tamer M. Fouad, Allen Chen, Hiroaki Akamatsu   +16 more
wiley   +1 more source

Editorial: Non-ionizing radiation: impacts on human health from exposures in occupational settings. [PDF]

Front Public Health
Modenese A, Nogueira CMCA, Wittlich M.
europepmc   +1 more source

CDK4/6 Inhibitors and Curcumin Synergistically Suppress HER2− Breast Cancer via Lethal ROS and Inhibition of Metastasis

Cancer Science, EarlyView.
Schematic illustrating that CDK4/6 inhibitors combined with curcumin induce lethal ROS accumulation by disrupting redox balance, downregulating GPX4, and depleting glutathione, leading to DNA damage and lipid peroxidation. This oxidative stress triggers tumor cell death and suppresses EMT‐driven migration.
Chenyu Wang, Yiqin Zou, Chunyu Chang, Siyue Liu, Xiankun Ke, Liang Hu, Di Wang, Yukang Lu, Shiwen Luo, Sijian Huang, Yilan Hu, Wenqi Yu, Aiping Deng, Ming Yue, Jue Jiang   +14 more
wiley   +1 more source

Biological Monitoring as a Preventive Occupational Healthcare Tool: Urinary Biomarkers of Benzene and Toluene Exposure Among Small-Scale Printing Workers in South Korea. [PDF]

Healthcare (Basel)
Hwang J, Kim Y, Kim I, Kim S, Hwang J, Park H, Kim KY.   +6 more
europepmc   +1 more source

Assessing the Quality of Transition Plans in Out‐of‐Home Care

Child &Family Social Work, EarlyView.
ABSTRACT Despite transition planning practices for young people (YP) in out‐of‐home care (OoHC), many continue to experience inequities after care, suggesting that intended outcomes are not being achieved. In Victoria, Australia, a Care and Transition Plan (transition plan(s)) document is the primary mandated tool to capture YP's transition goals ...
Hayley Wainwright, Melissa Savaglio, Sarah Morris, Danielle Newton, Ashlyn Devery, Joanne Luke, Sofia Grage‐Moore, Stephanie Gonsalves, Nick Halfpenny, Claire Nyblom, Catherine James, Philip Mendes, Helen Skouteris   +12 more
wiley   +1 more source