Results 261 to 270 of about 3,192,027 (387)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Seminars in epileptology: Presurgical epilepsy evaluation

open access: yesEpileptic Disorders, EarlyView.
Abstract All patients with drug‐resistant seizures benefit from a comprehensive evaluation to confirm their seizure diagnosis and explore surgical treatment options. This seminar in epileptology discusses advancements in the field and provides specific didactic material to create an active working knowledge for the care of patients with focal drug ...
Stephan Schuele   +11 more
wiley   +1 more source

A systematic survey of the measures used to identify postoperative changes in language function following epilepsy surgery

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy surgery, particularly dominant temporal lobe resection, poses a significant risk of post‐surgical language decline. There is considerable heterogeneity in the language assessment protocols employed across epilepsy surgery centers. This in turn is reflected in the observed variability in the incidence of language decline reported in ...
Isha Puntambekar   +3 more
wiley   +1 more source

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