Results 41 to 50 of about 303,769 (303)

5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux

Advanced Science, EarlyView.
Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li, Ping Deng, Tengfei Fan, Yuchen Qu, Miduo Tan, Yidan Liang, Peng Gao, Yongchun Peng, Mingke Qin, Sheng Jie, Rongrong Hao, Liting Wang, Lei Zhang, Chunhai Chen, Mindi He, Qinlong Ma, Yan Luo, Li Tian, Jia Xie, Mengyan Chen, Rui Tian, Min Li, Zhengping Yu, Zhou Zhou, Huifeng Pi   +24 more
wiley   +1 more source

Advanced Image‐Guidance and Surgical‐Navigation Techniques for Real‐Time Visualized Surgery

Advanced Science, EarlyView.
This review comprehensively summarizes advances in surgical navigation, covering both established and emerging intraoperative imaging technologies. It highlights mechanisms, advantages, limitations, and clinical applications, while emphasizing interdisciplinary collaboration.
Xiaoxiao Fan, Xiaolong Liu, Qiming Xia, Guoqiao Chen, Jiaxi Cheng, Zhaoqi Shi, Yifeng Fang, Parikshit Asutosh Khadaroo, Jun Qian, Hui Lin   +9 more
wiley   +1 more source

Ethics in occupational medicine

Indian Journal of Occupational and Environmental Medicine, 2009
Ethics, as a principle, is concerned with how people behave when they are faced with a conflict between two or more principles to which they subscribe. In Occupational Medicine, the doctor is concerned with the management, the workforce and his profession as a doctor. In most of the conflicts there is no single correct solution and the doctor must make
openaire   +4 more sources

Novel Role of Gut‐Derived Roseburia Intestinalis in Safeguarding Intestinal Barrier Integrity and Microenvironment Homeostasis During Arsenic Exposure

Advanced Science, EarlyView.
Arsenic exposure disrupts intestinal barriers and gut microenvironment. Fecal microbiota transplantation (FMT) alleviates arsenic‐induced damage, with gut‐derived Roseburia intestinalis (R.i) identified as a key protective strain. R.i administration counters arsenic toxicity through immunomodulatory pathways and metabolites.
Lixiao Zhou, Chunsong Wang, Jieying Gao, Xu Wu, Geng Li, Xuejun Jiang, Yinyin Xia, Jun Zhang, Bo Lv, Feng Zhao, Hongyang Zhang, Huifeng Pi, Jingfu Qiu, Shangcheng Xu, Zhen Zou, Chengzhi Chen   +15 more
wiley   +1 more source

Ever Smoking is Not Associated with Performed Spirometry while Occupational Exposure and Respiratory Symptoms are

International Journal of COPD, 2023
Linnea Carlsson,1,2 Mathias Holm,2 Maria Edlund,2 Magnus Ekström,3 Kjell Torén1,4 1Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg ...
Carlsson L, Holm M, Edlund M, Ekström M, Torén K   +4 more
doaj  

An anatomy of occupational medicine [PDF]

Occupational and Environmental Medicine, 1973
Lee, W. R. (1973). British Journal of Industrial Medicine, 30, 111-117. An anatomy of occupational medicine. Previous writers have attempted to describe occupational medicine by considering the functions of a doctor working in industry. In different communities, and even in the same community at different times, a doctor working in industry may ...
openaire   +3 more sources

Body Mass Index as a Potential Mediator of the Association Between Gout and Hypertension Among Chinese Older Adults: A Mediation Analysis in a Cross‐Sectional Study

AGING MEDICINE, EarlyView.
This study employed mediation analysis and found that BMI played a significant mediating role in the relationship between gout and hypertension. The mediating effect accounted for 12.59% of the total effect (ACME = 0.0244). ACME, average causal mediation effect.
Jia Wang, Jian‐bo Zhan, Lei Yi, Can Mei, Lin‐wanyue Chen, Gui‐ping Wang, Zi‐jun Shi, Wei‐ji Zhou, Chang‐e Xiong, Jing Cheng   +9 more
wiley   +1 more source

Analysis on Ga-Rak market workers' disease and treatment of Traditional Korean Medicine(TKM) (pilot study)

Journal of Pharmacopuncture, 2004
Objective : To broaden our understanding on occupational disease of market workers and to evaluate the effect of TKM treatment focusing on acupuncture and herb medicine and to promote base studies and clinical trials on occupational disease.
Yoo, Jae Ryong, Song, Ho Sueb
doaj   +1 more source

Long‐Term Nutritional Benefits of Laparoscopic Pancreatoduodenectomy Over Open Surgery

Annals of Gastroenterological Surgery, EarlyView.
Minimally invasive laparoscopic pancreaticoduodenectomy (LPD) significantly improves long‐term nutritional outcomes compared to open pancreaticoduodenectomy (OPD). LPD patients demonstrated better preservation of muscle mass index (PMI) and a lower incidence of postoperative fatty liver.
Koki Kurahashi, Takayuki Anazawa, Kei Yamane, Kazuyuki Nagai, Satoshi Ishida, Satoshi Ogiso, Yoichiro Uchida, Takashi Ito, Takamichi Ishii, Etsuro Hatano   +9 more
wiley   +1 more source