Results 61 to 70 of about 668,454 (306)

Relationships between brain activity, tryptophan-related gut metabolites, and autism symptomatology

open access: yesNature Communications
While it has been suggested that alterations in the composition of gut microbial metabolites may play a causative role in the pathophysiology of autism spectrum disorder (ASD), it is not known how gut microbial metabolites are associated with ASD ...
Lisa Aziz-Zadeh   +11 more
doaj   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

open access: yesAdvanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li   +10 more
wiley   +1 more source

Occupational Stress for Athletic Training Program Directors [PDF]

open access: yes, 2015
The roles and responsibilities for program directors of professional educational programs are numerous. The purpose of this study was to investigate how multiplicity of roles and responsibilities influence occupational stress.
Myers, Carrie B., Nynas, Suzette
core   +1 more source

Wide‐Range Adaptive Metal Oxide for Hydrogen Sulfide Detection From Earth to Space‐Like Environments

open access: yesAdvanced Science, EarlyView.
This work presents a gas sensing platform based on Cu‐doped SnO2 microspheres that operates reliably from ambient to space‐like conditions. The sensor maintains performance across vacuum and cryogenic environments, bypassing traditional oxygen‐mediated mechanisms, utilizing direct chemisorption and interfacial charge transfer.
Xi Chen   +9 more
wiley   +1 more source

Exposure to BDE-209 triggers necroptosis by activating the JAK2/STAT3 signaling pathway, thereby exacerbating neuroinflammation

open access: yesEcotoxicology and Environmental Safety
Polybrominated diphenyl ethers (PBDEs), a class of brominated flame retardants, are extensively employed in industrial applications. Among these, decabromodiphenyl ether (BDE-209), the predominant congener, is widely incorporated into consumer materials ...
Jing Yang   +6 more
doaj   +1 more source

Occupational Stress in Anaesthesia [PDF]

open access: yesAnaesthesia and Intensive Care, 1997
Anaesthetists, like most in the medical profession, often deny that they may be suffering from work-related stress. This article explores the sources and effects of occupational stress with suggestions for dealing with the stresses of our specialty.
openaire   +2 more sources

Job-related stress and burnout [PDF]

open access: yes, 2002
Occupational stress is a topic of substantial interest to organizational researchers and managers, as well as society at large. Stress arising from work conditions can be pervasive and significant in its impact on individuals, their families and ...
Cooper, Cary L.   +1 more
core   +1 more source

Elevated TRIM25 Impairs Poly (ADP‐ribose) Metabolism via PARG Degradation and Mediates Compression‐Induced Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
TRIM25 acts as a multifunctional hub driving intervertebral disc degeneration under mechanical stress. Mechanical compression significantly upregulates TRIM25 expression, establishing it as a key E3 ubiquitin ligase platform. TRIM25 targets PARG and Ku80 via distinct molecular interfaces, triggering their ubiquitination and degradation.
Zhangrong Cheng   +9 more
wiley   +1 more source

Role of calcium overload-mediated disruption of mitochondrial dynamics in offspring neurotoxicity due to methylmercury exposure during pregnancy and lactation

open access: yesEcotoxicology and Environmental Safety
Methylmercury (MeHg) is a potent neurotoxicant with neurodevelopmental toxicity that is widely ingested into the body through drinking water and food. MeHg crosses the placental barrier and accumulates in the brain of the fetus, affecting the growth and ...
Lingxu Kong   +6 more
doaj   +1 more source

Workplace bullying and task performance: A study on salespeople in retail industry [PDF]

open access: yesManagement Science Letters, 2018
Occupational stress has been known as a major cause of safety and health issues among sales people in retail organizations. Despite this, numerous studies have indicated the importance of factors and outcomes of occupational stress in several occupations,
Shi Min Chia, Daisy Mui Hung Kee
doaj   +1 more source

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