Results 161 to 170 of about 2,065,993 (355)

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

Advanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han, Jianhui Li, Yuting Zhu, Penghui Liu, Yaoyao Zheng, Muchun He, Bo Dong   +6 more
wiley   +1 more source

Sensitivity of Ocean Carbon Sink Estimates to Rare Observations

Geophysical Research Letters
We evaluate the impact of new data in the annual release of SOCATv2024 on air‐sea carbon dioxide (CO2) flux reconstructions. Using the pCO2‐Residual and LDEO‐HPD methods, we reconstruct surface ocean fCO2 based on SOCATv2023 and SOCATv2024.
Amanda R. Fay, Thea H. Heimdal, Viviana Acquaviva, Abby P. Shaum, Galen A. McKinley   +4 more
doaj   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

The fur seals and fur-seal islands of the North Pacific ocean

, 1898
George Clark, W. W. Duffield, David Starr Jordan, Frederic A. Lucas, Jefferson F. Moser, Joseph Murray, Leonhard Stejneger, C. H. T. Townsend, Leonhard Stejneger, Charles Haskins Townsend, Albatross (Steamer), U.S. Coast and Geodetic Survey   +11 more
openalex   +2 more sources

Visit to An Ocean Planet: Salinity and Deep Ocean Currents [PDF]

This resource uses text, images, maps and a laboratory exercise to explain how differences in the temperature and salinity of ocean water cause the formation of deep-ocean currents.

core  

Nanozyme‐Integrated Hydrogel Targeting AGEs for Diabetic Osteoarthritis Therapy

Advanced Science, EarlyView.
A nanozyme–integrated hydrogel (PTC‐MP) exhibiting with mild photothermal effects is constructed, and a “3R” (restrain‐restore‐reinforce) strategy is proposed for diabetic osteoarthritis (DOA) treatment based on advanced glycation end products (AGEs) targeting.
Rui Chen, Yanguo Su, Guiyuan Zhao, Jiaojiao Tao, Qijie Diao, Guangli Xiang, Tianze Jiang, Lu Han, Xia Zhao   +8 more
wiley   +1 more source

Ion‐Electron Fusion Transparent Film for Interactive Soft Robotics

Advanced Science, EarlyView.
An ion‐electron fusion transparent film with stable conductivity, high optical transmittance, and a broad linear strain‐sensing range of up to 300% is developed, attributed to the synergistic effects of ion penetration and microcrack design. When applied to soft robots, this film imparts proprioceptive sensing and underwater visible light communication
Zhiqiu Ye, Chao Zhang, Gaoyang Pang, Kaichen Xu, Shuangjia Liu, Yichen Wang, Jiahuan Qiu, Huaixuan Dai, Bingru Wang, Yinliang Gan, Liu Yang, Huayong Yang, Geng Yang   +12 more
wiley   +1 more source

Enhancement of primary production in the North Atlantic outside of the spring bloom, identified by remote sensing of ocean colour and temperature

, 2013
Gavin H. Tilstone, Peter I. Miller, Robert J. W. Brewin, Imants G. Priede   +3 more
openalex   +1 more source

Supplementary material to "Changes in the annual sea ice freeze-thaw cycle in the Arctic Ocean from 2001 to 2018"

, 2022
Na Li, Ruibo Lei, Mario Hoppmann, Donald K. Perovich, Hailun He   +4 more
openalex   +1 more source

A Scalable Method for Cavity‐Enhanced Solid‐State Quantum Sensors

Advanced Science, EarlyView.
Photoluminescent color centres in diamond and hexagon boron nitride are powerful nanoscale solid‐state quantum sensors. Methods for integrating them into macroscopic structures that improve their sensitivity are highly sought after. This study demonstrates a low‐cost and scalable method for the fabrication of quantum sensor‐doped thin‐film cavities ...
Daniel J. Tibben, Roy Styles, David A. Broadway, Jean‐Philippe Tetienne, Daniel E. Gómez, Philipp Reineck   +5 more
wiley   +1 more source