Results 101 to 110 of about 359,455 (303)

Computationally Efficient Modeling and Data Assimilation of Near-Surface Variability [PDF]

Near-surface (< 20m) ocean exhibits high variability due to coupled interactions, for e.g., with the atmosphere, sea ice, land, etc. Here we focus on atmospheric heat and momentum (wind) forcing, which are known to cause diurnal variability within the ...
Akella, Santha
core   +1 more source

Researchers explore Arctic freshwater\u27s role in ocean circulation [PDF]

, 2000
A critical, but insufficiently understood, component of global change is the influence of Arctic freshwater input on water mass exchange between the Arctic Ocean and Atlantic and Pacific Oceans.
Andrews, John T., Forman, Steven L., Lammers, Richard B., Lubinski, David, Maslowski, Wieslaw, Peterson, Bruce, Steele, Michael, Zhang, Jain   +7 more
core   +1 more source

O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer

Advanced Science, EarlyView.
This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu, Xueting Ren, Zhen Zhai, Lu Wang, Liang Liang, Zengqi Tan, Jiazhen Zhao, Yuxuan Han, Yuhan Li, Feng Guan, Xiang Li   +10 more
wiley   +1 more source

Adjoint‐Based Online Learning of Two‐Layer Quasi‐Geostrophic Baroclinic Turbulence

Journal of Advances in Modeling Earth Systems
For reasons of computational constraint, most global ocean circulation models used for Earth System Modeling still rely on parameterizations of sub‐grid processes, and limitations in these parameterizations affect the modeled ocean circulation and impact
F. E. Yan, H. Frezat, J. Le Sommer, J. Mak, K. Otness   +4 more
doaj   +1 more source

RENAL‐CHIP: Rejection Evaluation via Non‐Invasive Analysis of Circulating Podocytes With Herringbone‐Chip Isolation Platform

Advanced Science, EarlyView.
RENAL‐CHIP converts 1 mL of peripheral blood into a biopsy‐equivalent readout of renal‐allograft fate. By magnetic capture and release of donor‐derived circulating podocytes through a herringbone microfluidic chip, 84% capture, 96% release and single‐cell RNA evidence of rejection‐specific immunity are achieved.
Juan Song, Yilong Liu, Zeyuan Zheng, Ming Zhu, Yuning Zou, Pei Liu, Yue Zheng, Xiyuan Yu, Jianzhong Zheng, Chen Shao, Huimin Zhang, Chaoyong Yang   +11 more
wiley   +1 more source

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

Advanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei, Wenzhu Peng, Zekun Huang, Bingye Yang, Yiyu Wu, Minzhen Han, Yi Wang, Bingling Peng, Guosheng Hu, Jiawei Hong, Guijia Liu, Linwei Nie, Yang Gan, Miaoqin Huang, Xuan Luo, Weiwei You, Wen Liu, Caihuan Ke   +17 more
wiley   +1 more source

Polar Ocean Observations: A Critical Gap in the Observing System and Its Effect on Environmental Predictions From Hours to a Season

Frontiers in Marine Science, 2019
There is a growing need for operational oceanographic predictions in both the Arctic and Antarctic polar regions. In the former, this is driven by a declining ice cover accompanied by an increase in maritime traffic and exploitation of marine resources ...
Gregory C. Smith, Richard Allard, Marcel Babin, Laurent Bertino, Matthieu Chevallier, Matthieu Chevallier, Gary Corlett, Julia Crout, Fraser Davidson, Bruno Delille, Sarah T. Gille, David Hebert, Patrick Hyder, Janet Intrieri, José Lagunas, Gilles Larnicol, Thomas Kaminski, Belinda Kater, Frank Kauker, Frank Kauker, Claudie Marec, Claudie Marec, Matthew Mazloff, E. Joseph Metzger, Calvin Mordy, Anne O’Carroll, Steffen M. Olsen, Michael Phelps, Pamela Posey, Pierre Prandi, Eric Rehm, Phillip Reid, Ignatius Rigor, Stein Sandven, Matthew Shupe, Matthew Shupe, Sebastiaan Swart, Sebastiaan Swart, Ole Martin Smedstad, Amy Solomon, Andrea Storto, Pierre Thibaut, John Toole, Kevin Wood, Jiping Xie, Qinghua Yang, the WWRP PPP Steering Group   +46 more
doaj   +1 more source

Data management for JGOFS: Theory and design [PDF]

The Joint Global Ocean Flux Study (JGOFS), currently being organized under the auspices of the Scientific Committee for Ocean Research (SCOR), is intended to be a decade long internationally coordinated program. The main goal of JGOFS is to determine and
Bishop, James K. B., Flierl, Glenn R., Glover, David M., Paranjpe, Satish   +3 more
core   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

Near Real-Time Sub/Seasonal Prediction of Aerosol and Air Quality at the NASA Global Modeling and Assimilation Office [PDF]

Version 2 of the coupled modeling and analysis system used to produce near real time subseasonal to seasonal forecasts was released almost two years ago by the NASA/Goddard Global Modeling and Assimilation Office.
Colarco, Peter, Darmenov, Anton, Li, Zhao, Molod, Andrea   +3 more
core   +1 more source