Results 161 to 170 of about 56,682 (314)

Ferritin Iron Mineralisation: Route of Fe3+ Transfer From the Ferroxidase Centre to the Inner Cavity of Human H‐Chain Ferritin

open access: yesAngewandte Chemie, EarlyView.
Proposed mechanism for Fe3+ transport from the FoC (sites 1 and 2) of human H‐chain ferritin following oxidation of the di‐Fe2+ form. Glu61, aided by the flexibility of its sidechain, plays a key role in coordinating Fe3+ at three sites (3, 4 and 5) that mark out the transit route.
Zinnia Bugg   +3 more
wiley   +2 more sources

Adaptive Macroscopic Ensemble Allocation for Robot Teams Monitoring Spatiotemporal Processes

open access: yesAdvanced Intelligent Systems, EarlyView.
We propose an online, environment feedback‐driven macroscopic ensemble approach to adapt robot team task allocation in spatiotemporal environments by controlling robot populations rather than assigning individual robots, all while maintaining robust team performance even for small teams. Our simulation and experimental results show better or comparable
Victoria Edwards   +2 more
wiley   +1 more source

Incorporation of Novel Synthetic Glycolipids in Liposomal Nanoparticles Affects Opsonization and In Vivo Clearance

open access: yesAngewandte Chemie, EarlyView.
We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu   +18 more
wiley   +2 more sources

Liquid Jetting‐Based Miniature Robotic Navigation in Confined Fluidic Spaces

open access: yesAdvanced Intelligent Systems, EarlyView.
We introduce a new class of liquid‐jetting‐based miniature robots (JetBots) ranging in size from mm‐to‐cm, featuring a unified approach in design, fabrication, and actuation. They demonstrate fast locomotion (30.3 cm/s), rapid steering (648.8°/s), and diverse functions, such as puncturing soft materials and unlimited cargo sampling and delivery, paving
Debasish Roy, Tianlu Wang
wiley   +1 more source

Total Chemical Synthesis of Interleukin‐15 and Interleukin‐2: Taming Protein Hydrophobicity and Aggregation by a Versatile Solubilizing Strategy

open access: yesAngewandte Chemie, EarlyView.
A reducible solubilizing tag strategy (RST‐2.0) enables the synthesis, purification and ligation of difficult peptides while being readily removable just during folding, which overcomes the common challenges from protein hydrophobicity and aggregation. With this method, we achieved the first total synthesis of native and N‐glycosylated IL‐15 as well as
Jingwen Zeng   +4 more
wiley   +2 more sources

High‐elevation endemic plants predicted to lose habitat from changing climate in Washington State

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise High‐elevation plants face unique challenges from potential climate change impacts that will likely require upslope migration into increasingly smaller suitable habitat. This situation is particularly acute for endemic species that by definition occupy small geographic ranges.
Nicholas L. Gjording   +4 more
wiley   +1 more source

Sustainable Pd‐Catalyzed Aminations “on Dirty Water”

open access: yesAngewandte Chemie, EarlyView.
Aminations, done safely yet neat, and therefore, quickly, using low levels of Pd, in “dirty water” that must contain 30% KOH; not NaOH, and not at 5%,10%, 20%, 40%, or 50% KOH. Moreover, no base sensitivity of functional groups! Very cool. Thank you, Nature.
Erfan Oftadeh   +4 more
wiley   +2 more sources

NO NĀ PUA: Exploring the feasibility of culture‐based social prescribing on firefighters' wellbeing in Hawaiʻi

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract Firefighters face an array of stressors due to the demands of their occupation, leading to a high prevalence of mental health challenges. Social prescribing represents a novel approach to healthcare that emphasizes a holistic view of health and wellbeing.
Janice Ikeda   +2 more
wiley   +1 more source

Data-driven global ocean modeling for seasonal to decadal prediction. [PDF]

open access: yesSci Adv
Guo Z   +10 more
europepmc   +1 more source

A Global Prospective Harmonization Framework for Suicidality, Anhedonia, and Obsessive‐Compulsive Symptoms in Psychiatric Genetic Studies: A Cross‐Continental Study Within the Ancestral Population Network

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT This study aims to prospectively collect harmonized, quantitative, and dimensional psychiatric phenotypes (suicidality, anhedonia, and obsessive‐compulsive symptoms) and information on discrimination, stigma, and unfair treatment in up to 27,500 individuals across diverse ancestries and clinical populations for genetic analysis within the NIMH
Ana M. Diaz‐Zuluaga   +36 more
wiley   +1 more source

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