Results 1 to 10 of about 35,392 (211)

The Changing Landscape of Maintenance Therapy in Newly Diagnosed Multiple Myeloma: A Systematic Review With Network Meta-Analysis of the European Myeloma Network (EMN). [PDF]

Am J Hematol
Our meta‐analysis showed significant improvement of PFS with lenalidomide, proteasome inhibitors, and CD38‐based therapies. A significant OS benefit was noted only with lenalidomide in transplant‐eligible (TE) patients, while CD38‐directed therapy showed a trend toward improved OS.
Ludwig H, Terpos E, Gay F, van de Donk NWCJ, Bernhard S, Engelhardt M, Cook G, Schjesvold F, Einsele H, Jackson G, Pawlyn C, Mateos MV, Zweegman S, Schreder M, Beksaç M, Driessen C, Ocio EM, Popat R, Rasche L, Touzeau C, Musto P, Broijl A, Dimopoulos M, Hajek R, Boccadoro M, Sonneveld P.   +25 more
europepmc   +2 more sources

Minimally invasive characterization of peripheral blood measurable residual disease in multiple myeloma using high-sensitivity detection of ctDNA by next-generation sequencing. [PDF]

Hemasphere
Abstract Measurable residual disease assessment in bone marrow (BM‐MRD) is a crucial prognostic factor in multiple myeloma (MM), but its clinical use has some caveats, such as invasiveness, poor spatial representativity, and serial sampling. Novel minimally invasive approaches for monitoring peripheral residual disease (PRD) could facilitate its ...
Buenache N, Lasa M, Arroyo A, González C, Haertle L, Ruiz-Heredia Y, Ayala R, Alonso R, Martín-Muñoz A, Rosa-Rosa JM, González V, Calasanz MJ, Rodríguez-Otero P, Rosiñol L, De Arriba F, Ocio EM, Oriol A, González Y, Sureda A, Lakhwani S, Clavero ME, Ibáñez A, Gómez C, Orfao A, Mateos MV, Lahuerta JJ, Cedena MT, Bladé J, San Miguel J, Puig N, Paiva B, Martínez-López J.   +31 more
europepmc   +2 more sources

A critical analysis of the IMWG multiple myeloma complete response criterion in the era of mass spectrometry. [PDF]

Hemasphere
HemaSphere, Volume 10, Issue 2, February 2026.
Puig N, Agulló C, Paiva B, Cedena MT, Rosiñol L, Contreras T, Martínez-López J, Martínez-López J, Oriol A, Blanchard MJ, Ríos-Tamayo R, Sureda A, Lakhwani S, de la Rubia J, Cabañas V, de Arriba F, Paricio M, Iñigo MB, González-Calle V, Ocio EM, Castro S, Bargay J, Bladé J, San Miguel JF, Lahuerta JJ, Mateos MV.   +25 more
europepmc   +2 more sources

European Myeloma Network Group Consensus Statement on the use of next-generation sequencing for prognostic stratification of newly diagnosed multiple myeloma. [PDF]

Hemasphere
Abstract Given the evolving understanding of genetic risk factors in multiple myeloma (MM), this paper assesses whether next‐generation sequencing (NGS) could complement or even replace fluorescence in situ hybridization (FISH) at diagnosis. A structured consensus process within European Myeloma Network (EMN) clinical and laboratory groups was ...
Bolli N, D'Agostino M, Bagratuni T, Boccadoro M, Cavo M, Driessen C, Einsele H, Engelhardt M, Gay F, Gutiérrez NC, Hájek R, Holien T, João C, Kaiser M, Kortüm KM, Leypoldt L, Moreau P, Musto P, Ocio EM, Raab MS, Rasche L, Schjesvold F, Sevcikova T, Terpos E, Touzeau C, Van de Donk NWCJ, van Duin M, Weisel K, Zamagni E, Cupedo T, Sonneveld P, Terragna C.   +31 more
europepmc   +2 more sources

European Expert Panel Consensus on Outpatient Administration of Teclistamab and Talquetamab in Patients With Multiple Myeloma: Feasibility, Key Considerations, and Future Directions. [PDF]

Eur J Haematol
ABSTRACT Objectives Teclistamab and talquetamab treatments are typically initiated in a hospital due to the potential risk of cytokine release syndrome. However, emerging data support the potential for outpatient administration (i.e., administration without overnight hospital admission).
Lund T, Khandanpour C, Anguille S, Kisro J, Krauth MT, Lund J, Nijhof I, Ocio EM, Zamagni E, Javelot M, Albrecht C, Cerezo CE, Perrot A.   +12 more
europepmc   +2 more sources

Is OCIO superior in asset allocation performance?

Journal of Derivatives and Quantitative Studies, 2023
This study aims to empirically analyze the asset allocation capabilities of Outsourced Chief Investment Officers (OCIOs) in Korea. The empirical analysis used data from 35 funds that were evaluated by the Ministry of Strategy and Finance from 2012 to 2020. The results of the analysis are summarized as follows.
Kang, Myungjoo, Song, Inwook, Kim, Sei-Wan   +2 more
exaly   +4 more sources

Ocio productivo, entretenimiento e industria cultural: del ocio tradicional al ocio digital. [PDF]

Management Review, 2017
Este artí­culo tiene como propósito mostrar los cambios que ha sufrido el concepto de ocio desde los griegos hasta la actualidad, estableciendo sus usos y alcances. Adicionalmente, se aborda el papel que jugaron las nuevas tecnologí­as y sus repercusiones en la industria del entretenimiento o industrial cultural, resaltando la justificación del ocio ...
Primo Tapia, Wilfrido de Jesús
openaire   +2 more sources

Del ocio al negocio… y otra vez al ocio [PDF]

Papers. Revista de Sociologia, 1997
Through the history of social thought the dicotomic relationship between leisure and business is analysed in terms of activity and use of time.
openaire   +4 more sources

RECREACIÓN, OCIO Y ANTROPOTÉCNICA

Impetus, 2016
Este escrito tiene por objeto exponer el sentido de la ociosidad como antropotécnica, esto es, como una forma de ejercicio a través de la cual el hombre se construye y modifica a sí mismo. En la primera parte, se presenta una problematización sobre la diferencia entre recreación y ocio.
Díaz Velasco, Andrés, Guerrero Reyes, Carolina   +1 more
openaire   +2 more sources

Crisis epilépticas en niños con síndrome de Dravet en condiciones de calor extremo: estudio cualitativo de la perspectiva de los progenitores

Developmental Medicine &Child Neurology, Volume 68, Issue 10, Page e168-e178, October 2026.
Resumen Objetivo Describir la experiencia de progenitores de niños y adolescentes con síndrome de Dravet en relación con el impacto de las olas de calor o las altas temperaturas ambientales en las crisis epilépticas de sus hijos, así como las estrategias de afrontamiento empleadas.
Angel Aledo‐Serrano, José Ángel Aibar, Domingo Palacios‐Ceña, Maria Salcedo‐Perez‐Juana, Maria Palacios‐Ceña, Simona Giorgi, Manuel Lorenzo‐Dieguez, Sanjay M Sisodiya, Cristina García‐Bravo   +8 more
wiley   +1 more source