Results 71 to 80 of about 35,820 (263)

Semantic Text Segmentation from Synthetic Images of Full-Text Documents

Информатика и автоматизация, 2019
An algorithm (divided into multiple modules) for generating images of full-text documents is presented. These images can be used to train, test, and evaluate models for Optical Character Recognition (OCR).
Lukáš Bureš, Ivan Gruber, Petr Neduchal, Miroslav Hlaváč, Marek Hrúz   +4 more
doaj   +1 more source

Uhrf1‐Mediated PKM2 Degradation via Ubiquitination Alleviates Inflammation and Pyroptosis in Inflammatory Bowel Disease

Advanced Science, EarlyView.
Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.
Juan Zhang, Xin‐Rong Xu, Hui‐Lin Zhang, Qi‐Meng Zhu, Xin‐Yuan Li, Xi‐Peng Shang, Jing‐Hui Du, Christophe Morisseau, Feng Qiu, Cheng‐Peng Sun   +9 more
wiley   +1 more source

AARS1‐Mediated H3K27 Lactylation Rewires Glycolysis to Sustain Aggressive and Recurrent Bladder Cancer

Advanced Science, EarlyView.
AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.
Qin Yuan, Tianbao Song, Yipeng He, Sihan Xia, Yaoqiu Huang, Wenlin He, Qin Yi, Zefeng Wang, Peihan Wang, Chenbo Huang, Linzhi Li, Zhen Yin, Fan Cheng, Weimin Yu   +13 more
wiley   +1 more source

From Paginā to Webpage: On Developing and Documenting a Digitized Latin Collection

Journal of Open Humanities Data
In this work, we present three Zenodo repositories related to the creation of digital editions for Latin texts. The first is the Notre Dame Digitized Latin Collection (ND-DLC), which contains over 550,000 words of Latin in TEI-XML.
Stephen Bothwell, Kaitlin Stephan, Hildegund Müller, David Chiang   +3 more
doaj   +1 more source

Automation of PostOCR error correction in the digitization of historical texts [PDF]

Computer Science Journal of Moldova
Processing texts from distant historical periods, especially those handwritten in languages with low computational resources, presents significant challenges. Even if modern methods make it possible to achieve, after laborious machine learning procedures,
Tudor Bumbu , Liudmila Burtseva, Svetlana Cojocaru, Alexandru Colesnicov, Ludmila Malahov   +4 more
doaj   +1 more source

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

Automatic Text Recognition in Cultural Heritage Institutions. Survey Results

Journal of Open Humanities Data
This dataset was collected during a survey exploring the use of Automatic Text Recognition (ATR) in cultural heritage institutions. The anonymised dataset, stored in the British Library Repository, investigates how ATR has been integrated into ...
Valentina Vavassori
doaj   +1 more source

Epigenetic Reactivation of TNFRSF19 Suppresses Mitophagy and Sensitizes Triple‐Negative Breast Cancer to Doxorubicin

Advanced Science, EarlyView.
TNFRSF19 is an epigenetically silenced regulator of mitophagy in triple‐negative breast cancer. TNFRSF19 deficiency activates the TGFBR1–SMAD3–PINK1 axis to promote mitophagy and confer doxorubicin resistance, whereas decitabine‐mediated restoration of TNFRSF19 suppresses mitophagy and enhances doxorubicin sensitivity, revealing a targetable epigenetic–
Shiyang Liu, Chenguang Liu, Weihong Zheng, Xiaofei Tong, Zhengwei Gui, Zonghong Lu, Sun Ieong, Lin Zhang   +7 more
wiley   +1 more source

Automatic Classification and Semantic Retrieval for Low-Resource Parliamentary Archives: A Case Study of the DRC Senate

Journal of Applied Informatics and Computing
Parliamentary archives preserve the administrative, legal and political memory of legislative institutions. At the Senate of the Democratic Republic of the Congo, many documents are scanned PDF files, which makes manual indexing, classification and ...
Otshudiakoy Jean, Djungu Ahuka Saint Jean   +1 more
doaj   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source