Results 231 to 240 of about 2,567,695 (339)
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song+24 more
wiley +1 more source
Multi modal optical coherence tomography flowmetry of organ on chip devices. [PDF]
Tugberk D+6 more
europepmc +1 more source
The Rorschach Ink-blot Test: II. (Brit. Journ. Med. Psychol., vol. xiii, Oct., 1933.) Vernon, Philip E. [PDF]
John D. W. Pearce
openalex +1 more source
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang+11 more
wiley +1 more source
Catheter-based polarimetric imaging to complement MRI for deep brain stimulation neurosurgery. [PDF]
Masoumi S+7 more
europepmc +1 more source
Pulso Semanal (14 oct-18 oct, 2019)
Publicación que presenta una síntesis de las principales noticias y sucesos de los mercados financieros y bursátiles del mundo ocurridos en la última semana.
openaire +1 more source
Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice
PSTNVglut2 neurons function as a new central baroreflex hub via projections to the NTS, modulating parasympathetic cardiac output to maintain cardiovascular homeostasis while synchronously regulating locomotion. Blood pressure fluctuations negatively correlate with locomotor performance.
Ming‐Xuan Lu+8 more
wiley +1 more source
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang+9 more
wiley +1 more source