Results 251 to 260 of about 455,543 (293)

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti‐CEACAM5 CAR T‐Cell Efficacy Against Colorectal Cancer

Advanced Science, EarlyView.
This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik, Christopher J. Ward, Soura Chakraborty, Ziwei Zhang, Daniel Heraghty, Prasanna Suresh, Bing Li, Shekhar Kedia, Jhuma Pramanik, Simon J. Davis, James P. Roy, Michael A. Chapman, Bidesh Mahata, David Klenerman   +13 more
wiley   +1 more source

Best Practices for High-Quality Anterior Segment Optical Coherence Tomography Imaging of Eyes with the Port Delivery Platform Implant. [PDF]

Diagnostics (Basel)
Emanuelli A, Ohr M, Castro J, Laoprasert R, Prager A, Latkany P, Jaffe GJ.   +6 more
europepmc   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

Optical Coherence Tomography in Acute Coronary Syndromes. [PDF]

Rev Cardiovasc Med
Synetos A, Koliastasis L, Ktenopoulos N, Aghayan S, Katsaros O, Vlasopoulou K, Drakopoulou M, Apostolos A, Kachrimanidis I, Vlachakis PK, Tolis E, Latsios G, Tsioufis K, Toutouzas K.   +13 more
europepmc   +1 more source

Development of Teleoperated Robotic System for Remote Intraocular Microsurgery

Advanced Science, EarlyView.
A teleoperated robotic system, characterized by micrometer‐scale precision and a remote center of motion design, is developed and validated to ensure the safety and flexibility of remote intraocular surgery. This system exhibits superior performance in experimental evaluations and holds significant potential for advancing remote microsurgery ...
Andi Xu, Zhangkai Lian, Wenben Chen, Yanlin Li, Jiali Liu, Hongli Liang, Rihui Song, Zikai Lin, Mingyuan Li, Yining Huang, Ling Jin, Zheming Zhang, Xiaoyue Wei, Bingqian Liu, Wei Ma, Tao Li, Hang Shao, Wei Liu, Kun Gao, Xin Zhang, Pisong Yan, Ruiyang Li, Ruixin Wang, Xiaohang Wu, Duoru Lin, Xiang Chen, Jinghui Wang, Xingwu Zhong, Mohammad Ali Nasseri, Kai Huang, Haotian Lin   +30 more
wiley   +1 more source

Ocular massage in central retinal artery occlusion: Monitoring vascular recovery with optical coherence tomography angiography - A case series. [PDF]

Am J Ophthalmol Case Rep
Rizzo C, Mercuri S, Lavia C, Viggiano P, Virgili G, Giansanti F, Faraldi F, Bacherini D.   +7 more
europepmc   +1 more source

Acute zonal occult outer retinopathy complex and angioid streaks: a case report. [PDF]

Int J Ophthalmol
Liu ZY, Zhang H, Sun XL, Peng XY.
europepmc   +1 more source

Depth-Resolved OCT of Root Canal Walls After Diode-Laser Irradiation: A Descriptive Ex Vivo Study Following a Stereomicroscopy Report. [PDF]

Diagnostics (Basel)
Stănuşi AŞ, Diaconu OA, Stănuşi A, Osiac E, Brătoiu MR, Petrescu GS, Bugălă AS, Dimitriu B, Ţuculină MJ.   +8 more
europepmc   +1 more source

Automated geographic atrophy detection in OCT volumes

, 2018
Qi Yang, Ying Dong, Kanichi Tokuda, Taiki Aimi, Masahiro Akïba, José M. Ruiz‐Moreno, Charles Reisman   +6 more
openalex   +1 more source