Mass spectrometry in ocular drug research
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo+6 more
wiley +1 more source
Distinctive Mechanisms and Patterns of Exudative Versus Tractional Intraretinal Cystoid Spaces as Seen With Multimodal Imaging. [PDF]
PurposeTo determine clear-cut distinctions between tractional and exudative intraretinal cystoid spaces subtypes.DesignRetrospective, multicenter, observational case series.MethodsA cohort of patients diagnosed with intraretinal cystoid spaces and imaged
Au, Adrian+9 more
core
Long-term rearrangement of retinal structures in a novel mutation of X-linked retinoschisis [PDF]
The aim of the present study was to report a novel mutation in the retinoschisin 1 (RS1) gene in a Caucasian family affected by X-linked juvenile retinoschisis (XLRS) and to describe the long-term modification of retinal structure.
Colavito, Davide+7 more
core +1 more source
Swept source optical coherence tomography-angiography (OCT-angiography) gives us a unique opportunity to study the vasculature of choroidal lesions in vivo. We describe the OCT angiographic characteristics of circumscribed choroidal hemangioma before and
Rohan Chawla+3 more
doaj +1 more source
Differential intensity contrast swept source optical coherence tomography for human retinal vasculature visualization [PDF]
We demonstrate an intensity-based motion sensitive method, called differential logarithmic intensity variance (DLOGIV), for 3D microvasculature imaging and foveal avascular zone (FAZ) visualization in the in vivo human retina using swept source optical ...
Fraser, Scott, Motaghiannezam, Reza
core +1 more source
Choroidal nevus and polypoidal vasculopathy: case series
Background To report an association between choroidal nevus and polypoidal choroidal vasculopathy (PCV) in three patients. Case presentation We have encountered 3 isolated patients in our center presenting with subretinal exudation and a choroidal nevus ...
Karlos Ítalo S. Viana+3 more
doaj +1 more source
OCT-angiography: A qualitative and quantitative comparison of 4 OCT-A devices
Purpose To compare the quality of four OCT-angiography(OCT-A) modules. Method The retina of nineteen healthy volunteers were scanned with four OCT-devices (Topcon DRI-OCT Triton Swept-source OCT, Optovue RTVue-XR, a prototype Spectralis OCT2, Heidelberg ...
M. Munk+6 more
semanticscholar +1 more source
Purpose To compare postvitrectomy retinal and choroidal vessel density (VD) and retinal layer thickness between eyes with macula-off and macula-on rhegmatogenous retinal detachment (RRD) using swept-source optical coherence tomography (SS-OCT) and ...
E. Hong+5 more
semanticscholar +1 more source
Wide-Field OCT Angiography at 400 KHz Utilizing Spectral Splitting
Optical angiography systems based on optical coherence tomography (OCT) require dense sampling in order to maintain good vascular contrast. We demonstrate a way to gain acquisition speed and spatial sampling by using spectral splitting with a swept ...
Laurin Ginner+5 more
doaj +1 more source
In vivo high-contrast imaging of deep posterior eye by 1-um swept source optical coherence tomography and scattering optical coherence angiography [PDF]
Retinal, choroidal and scleral imaging by using swept-source optical coherence tomography (SS-OCT) with a 1-μm band probe light, and high-contrast and three-dimensional (3D) imaging of the choroidal vasculature are presented.
Akiba Masahiro+7 more
core +1 more source