Results 41 to 50 of about 9,478 (255)

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

The hidden charm pentaquarks are the hidden color-octet uud baryons?

open access: yesPhysics Letters B, 2017
The I(JP)=12(12−), 12(32−), and 12(52−) uudcc‾ pentaquarks are investigated by the quark cluster model. This model, which reproduces the mass spectra of the color-singlet S-wave q3 baryons and qq‾ mesons, also enables us to evaluate the quark interaction
Sachiko Takeuchi, Makoto Takizawa
doaj   +1 more source

Singlet-octet-glueball mixing of scalar mesons

open access: yesPhysics Letters B, 2022
The mixing angles between scalar isoscalar resonances and a scalar glueball are determined from their decays into two pseudoscalar mesons. For f0(1370) and f0(1500), at most a small glueball component is admitted by the data. The decay modes of f0(1710),
E. Klempt, A.V. Sarantsev
doaj   +1 more source

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

open access: yesAdvanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li   +8 more
wiley   +1 more source

Quantum coherence, top transverse polarisation and the Tevatron asymmetry AFBℓ

open access: yesPhysics Letters B, 2014
We revisit the relation between the asymmetries AFB and AFBℓ in tt¯ production at the Tevatron, using as new physics benchmark a colour octet. We find that AFBℓ receives large contributions from the interference between λ=±1/2 top helicity states, which ...
J.A. Aguilar-Saavedra
doaj   +1 more source

Nanoparticle Adjuvant Design Enhances Germinal Center Responses Targeting Conserved Subdominant Epitopes for Pan‐Coronavirus Vaccine Development

open access: yesAdvanced Science, EarlyView.
Current SARS‐CoV‐2 vaccines generate short‐lived, strain‐specific immunity. A polymeric TLR7 agonist nanoparticle (TLR7‐NP) adjuvant enhances lymph node targeting and promotes early and sustained germinal center responses toward conserved S2 epitopes of the spike protein.
Sijin Huang   +12 more
wiley   +1 more source

Neutron Electric Dipole Moment from colored scalars⋆

open access: yesEPJ Web of Conferences, 2014
We present new contributions to the neutron electric dipole moment induced by a color octet, weak doublet scalar, accommodated within a modified Minimal Flavor Violating framework.
Fajfer Svjetlana, Eeg Jan O.
doaj   +1 more source

Optimizing printing parameters for enhanced mechanical properties of 3D printed PLA octet lattice structures

open access: yesEuropean Mechanical Science, 2023
This study explores the impact of printing parameters on the mechanical properties of 3D printed octet lattice structures using PLA material. Focused on optimizing layer height, print speed, and infill density, the study employed Taguchi methodology ...
Oğuz Tunçel
doaj   +1 more source

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

open access: yesAdvanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang   +27 more
wiley   +1 more source

Deep Learning‐Assisted Design of Mechanical Metamaterials

open access: yesAdvanced Intelligent Discovery, EarlyView.
This review examines the role of data‐driven deep learning methodologies in advancing mechanical metamaterial design, focusing on the specific methodologies, applications, challenges, and outlooks of this field. Mechanical metamaterials (MMs), characterized by their extraordinary mechanical behaviors derived from architected microstructures, have ...
Zisheng Zong   +5 more
wiley   +1 more source

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