Results 51 to 60 of about 9,478 (255)

A Murine Bispecific Antibody Efficiently Redirects T Cells Against Calr Mutated Stem Cells In Vivo

American Journal of Hematology, EarlyView.
ABSTRACT Calreticulin (CALR) mutations are prevalent in 20%–30% of patients with BCR::ABL1‐negative myeloproliferative neoplasms (MPN). Mutant calreticulin (mutCALR), presented by the thrombopoietin receptor (MPL, also known as TPOR or CD110) on the surface of the disease‐initiating MPN progenitors, represents an ideal target for curative ...
Shengen Xiong, Tamara Wais, Cecilia Varga, Christina Schueller, Sarada Achyutuni, Robert Kralovics   +5 more
wiley   +1 more source

A description of χ cJ → VV decays within the effective field theory framework

Journal of High Energy Physics
We study χ cJ → VV decays using the QCD effective field theory approach. The helicity suppressed decay amplitudes are also considered. The colour-singlet contributions of these amplitudes suffer from the endpoint singularities, it is shown that they can ...
Nikolay Kivel
doaj   +1 more source

Influence of Infill Design in Fabrication of 3D-printed PLA Parts Using FDM

Medžiagotyra
The present work examines the mechanical characteristics of polylactic acid (PLA) samples manufactured in 3D printing using various infill patterns. The infill patterns investigated are cuboid, grid, and octet, prepared at a constant infill density of 50
Tamilanban THANGARAJU, Pankaj KUMAR, Dhanesh Babu SAMUEL DHANASEKARAN, Ganesh Babu LOGANATHAN, Bhavya PAPE GOWDA, Thenmozhi SIVAKUMAR, Nafeez Ahmed LIYAKAT   +6 more
doaj   +1 more source

Investigation of Hexagonal Honeycomb Topology for Impact Optimization in Energetic Material

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The regulation of the mechanical properties of energetic materials manufactured by traditional processes is constrained. However, the introduction of lattice structures can facilitate the regulation of mechanical properties without necessitating alterations to the materials themselves. Using finite element analysis and experimental validation,
Xueye Chen, Bin Yang, Linna Zhang, Zhihao Ding, Weitao Yang   +4 more
wiley   +1 more source

Transient Transfection of Rolling‐Circle Amplified DNA in Biomanufacturing‐Relevant Mammalian Cell Lines: A Comparison of Transfection Conditions for Optimal Protein Expression

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Rolling‐circle amplification (RCA) is a completely synthetic and rapid mechanism for scaling‐up bulk DNA that eliminates requirements for large‐scale bacterial fermentation. Several reports have described the surprising ability of large unprocessed (hyperbranched) rolling circle‐amplified DNA (RCA DNA) to effectively transfect cultured cells ...
Evelina Loghin, Erik Kvam, Lisa Lowery, Nathan Hudson, Jenny Keen, Brian Davis, Roger B. Dodd, Christine Surrette, John Nelson   +8 more
wiley   +1 more source

Lab‐Scale Continuous Biomanufacturing: A Tool for Process Development With Adaptive Strategies for Capture and Virus Inactivation

Biotechnology and Bioengineering, EarlyView.
Schematic representation of the continuous lab‐scale process. ABSTRACT Monoclonal antibodies (mAbs) are nowadays fundamental in treating a wide range of severe diseases, including cancer, infections, or autoimmune disorders. Due to their high specificity, potent activity, and fewer side effects compared to small molecular drugs, the market for mAbs is ...
Thomas Kruse, Fabian Schmitz, Janina Kilian, Jonas Austerjost, Lucas‐Nik Reger, Markus Kampmann   +5 more
wiley   +1 more source

Enhancing CHO cell recombinant protein production using a perfusion‐directed host evolution approach

Biotechnology Progress, EarlyView.
Abstract Clonally derived cell lines generated from Chinese hamster ovary (CHO) cells encounter numerous stressors when cultured in high‐intensity perfusion bioreactors leading to poor process performance. To circumvent this, the ability of CHO cells to adapt to different culture environments was exploited. Here host cells were selected in the presence
Peter Amaya, Rajesh K. Mistry, Susie Sou, Sonja Hess, Bijay Khanal, Zayla Schaeffer, Jie Zhu, Lina Chakrabarti   +7 more
wiley   +1 more source

Single-spin asymmetries in $$p^\uparrow p \rightarrow J/\psi +X$$ p↑p→J/ψ+X within a TMD approach: role of the color octet mechanism

European Physical Journal C: Particles and Fields, 2019
We calculate the transverse single-spin asymmetry (SSA) for $$J/\psi $$ J/ψ production in proton-proton collisions, within non-relativistic QCD, employing the transverse momentum dependent, generalized parton model, which includes both spin and intrinsic
Umberto D’Alesio, Francesco Murgia, Cristian Pisano, Sangem Rajesh   +3 more
doaj   +1 more source

The violin octet [PDF]

The Journal of the Acoustical Society of America, 1983
Eight new violin family instruments in graduated sizes project the tone quality of the violin into seven other tone ranges, representing the first time a consistent theory of acoustics has been applied to a family of musical instruments. Undertaken in 1956 at the instigation of Henry Brant, they resemble instruments constructed in Europe during the ...
openaire   +1 more source

High Pressure Stabilizes the Elusive Hexacoordinated Carbon

ChemistryEurope, EarlyView.
The MCF6 species (M = Ca, Sr) is more stable than the bicomponent MF2…CF4 mixture in the solid‐state at high pressure (p > 400 GPa). The main building block is the [CF6]2− unit in which carbon is hexacoordinated. Unusually high coordination number for elements has been of great interest in chemistry.
Shovan Das, Adrish Das, Ayan Datta
wiley   +1 more source