Results 31 to 40 of about 5,246,989 (312)

The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells [PDF]

, 2008
The protein product of the ocular albinism type 1 gene, named OA1, is a pigment cell-specific G protein-coupled receptor exclusively localized to intracellular organelles, namely lysosomes and melanosomes.
Bennett, DC, Venturi C, Palmigiano, A, Schiaffino, MV, Piccirillo, R, Altimare D., Rotondo G., Tacchetti, C, Marigo, V, Bagnato P., Coppola M., Rotondo, G, Venturi, C, Sviderskaya, EV, Palmisano I., Palmigiano A., Altimare D, Bagnato, P, Marigo V., Surace, EM, Altimare, D, Tacchetti C, Innamorati G., Venturi C., Surace E. M., Palmisano I, Rotondo G, INNAMORATI, Giulio, BALLABIO, ANDREA, Schiaffino M. V., Sviderskaya E. V., Palmigiano A, Innamorati G, SURACE, Enrico Maria, Sviderskaya EV, Piccirillo R, Bagnato P, Ballabio A., Incerti B, Piccirillo R., Tacchetti C., Schiaffino MV, Coppola, M, Incerti, B, Bennett DC, Incerti B., Palmisano, I, Coppola M, Bennett D. C., Innamorati, G, Ballabio, A, Marigo V   +51 more
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Surveillance for ocular hypertension : an evidence synthesis and economic evaluation [PDF]

, 2012
OBJECTIVES: To determine effective and efficient monitoring criteria for ocular hypertension [raised intraocular pressure (IOP)] through (i) identification and validation of glaucoma risk prediction models; and (ii) development of models to determine ...
Banister, K, Burr, JM, Kotecha, A, Garway-Heath, D., H Lemij, M Ryan, Tuulonen, A., Vale, L., Fraser, C., R Sanders, Crabb, D, Kotecha, A., Cook, J, Y Takwoingi, S Vernon, Takwoingi, Y., Banister, K., Fraser, C, Deeks, J, Sanders, R, A Tuulonen, Cook, J., Hernández, R, Glasziou, P, Tuulonen, A, Lemij, H., Vale, L, Burr, Jennifer Margaret, Elders, A., Burr, J.M., R Asaoka, Takwoingi, Y; id_orcid, Azuara-Blanco, A, P Glasziou, Botello-Pinzon, P, Garway-Heath, D, Ryan, Mandy, Vazquez-Montes, M, Lemij, H, Deeks, J., Takwoingi, Y, D Crabb, Azuara-Blanco, A.; id_orcid, L Vale, A Azuara-Blanco, Perera, R., Ryan, M, van der Schoot, J, Perera, R, Sanders, R., Crabb, D., Elders, A, D Garway-Heath, Ryan, M., R Hernández, K Banister, C Fraser, J Cook, J van der Schoot, Botello-Pinzon, P., A Elders, A Kotecha, Glasziou, P., Azuara-Blanco, A., King, A., J Deeks, JM Burr, A King, Burr, J M, Glasziou, Paul, King, A, Vernon, S, Asaoka, R., Vazquez-Montes, M., van der Schoot, J., Vernon, S., M Vazquez-Montes, Perera, Rafael, R Perera, Asaoka, R, Hernandez, R., P Botello-Pinzon, Azuara-Blanco, Augusto; id_orcid, King, Anthony J, Deeks, Jonathan J, Burr, Jennifer M, Azuara-Blanco, Augusto, Botello, Adriana P, Sanders, Roshini, Takwoingi, Yemisi, Garway-Heath, David F, Takwoingi, Yemisi; id_orcid, Lemij, Hans G   +92 more
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Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

The role of inflammation and fibroblasts in conjunctival scarring in ocular mucous membrane pemphigoid [PDF]

, 2009
Ocular mucous membrane pemphigoid (ocular MMP) is a visually devastating disease where up to 30% of patients become blind due to the consequences of conjunctival inflammation and aggressive fibrosis.
Saw, V.P.J.
core  

Clinical course of ocular Behcet's disease in siblings

, 2001
Purpose: Familial occurrence has been reported in approximately 8% of Turkish patients with Behcet's disease. Our aim was to compare the clinical course of ocular Behcet's disease among siblings. Methods: We retrospectively studied five pairs of siblings
Gul, A, Urgancioglu, M, Tuga-Tutkun, I, Onal, S   +3 more
core   +1 more source

Metabolomic insights into vitreous humor with therapy outcome in type 2 diabetic retinopathy

BMC Ophthalmology
Background The therapeutic outcome for Type 2 Diabetic Retinopathy (T2DR) following vitrectomy has been unsatisfactory, with no definitive biomarker available to predict treatment response.
Yuxu Hao, Xiangjun She, Gongyu Huang, Xuyang Chu, Shixin Zhao, Zhe Lv, Jiwei Tao, Yun Zhang   +7 more
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Central network changes in patients with advanced monocular blindness: A voxel‐based morphometric study

Brain and Behavior, 2019
Objective To study the changes in gray matter volume (GMV) in patients with advanced monocular blindness (MB) using voxel‐based morphometry (VBM). Methods Thirty‐one patients with advanced MB (25 males and six females) and 31 normal controls (25 males ...
Wen‐Qing Shi, Yin He, Qing‐Hai Li, Li‐Ying Tang, Biao Li, Qi Lin, You‐Lan Min, Qing Yuan, Pei‐Wen Zhu, Rong‐Bing Liang, Yi Shao   +10 more
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Ocular rosacea

, 2005
Rosacea is a common skin disease that frequently involves the eye. Although the pathogenesis of the disease remains undefined, recent findings suggest that an altered inflammatory response plays an important role in both cutaneous and ocular rosacea ...
Mannis, Mark J. [UNIFESP], Alvarenga, Lênio Souza [UNIFESP]   +1 more
core   +1 more source