Results 141 to 150 of about 1,264,680 (377)

Midkine‐Mediated Microglia Activation after Renal Injury Promotes Cognitive Impairment Following Ischemic Renal Injury

open access: yesAdvanced Science, EarlyView.
The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu   +10 more
wiley   +1 more source

Hypoperfusive and hypertensive ocular manifestations in Takayasu arteritis

open access: yesClinical Ophthalmology, 2010
Jayanthi Peter1, Sarada David1, George Joseph2, Saban Horo1, Debashish Danda31Department of Ophthalmology, Schell Eye Hospital, Vellore, India; 2Department of Cardiology, Christian Medical College Hospital, Vellore, India; 3Department of Clinical ...
Jayanthi Peter   +2 more
doaj  

Bilateral Exudative Retinal Detachment in a Young Patient with Chronic Renal Failure

open access: yesInternational Medical Case Reports Journal, 2021
Olufunmi Adebimpe Ijeoma Otuka,1 Lisa Ifenyinwa Eweputanna,2 Nneka Chioma Okoronkwo,3 Anya Kalu1 1Ophthalmology Unit, Department of Surgery, Abia State University Teaching Hospital, Aba, Abia State, Nigeria; 2Department of Radiology, Abia State ...
Otuka OAI   +3 more
doaj  

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha   +13 more
wiley   +1 more source

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

open access: yesAdvanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang   +15 more
wiley   +1 more source

A patient preference comparison of Azarga™ (brinzolamide/timolol fixed combination) vs Cosopt® (dorzolamide/timolol fixed combination) in patients with open-angle glaucoma or ocular hypertension

open access: yesClinical Ophthalmology, 2008
Thomas K Mundorf1, Steven H Rauchman2, Robert D Williams3, Ricardo Notivol4, Brinzolamide/Timolol Preference Study Group51Mundorf Eye Center, Charlotte, NC, USA; 2North Valley Eye Medical Group, Mission Hills, CA, USA; 3Taustine Eye Center, Louisville ...
Thomas K Mundorf   +4 more
doaj  

Prevalence of glaucoma and characteristics of ocular manifestations in patients with Naevus of Ota

open access: yesBMJ Open Ophthalmology
Aims This cross-sectional study aimed to determine the prevalence of glaucoma and associated ocular characteristics in Thai patients with Naevus of Ota, comparing those with ocular melanocytosis or oculodermal melanocytosis to those exhibiting only skin ...
Woraphong Manuskiatti   +6 more
doaj   +1 more source

Comparison of Newly Diagnosed Ocular Hypertension and Open-Angle Glaucoma: Ocular Variables, Risk Factors, and Disease Severity [PDF]

open access: gold, 2011
Yvonne M. Buys   +10 more
openalex   +1 more source

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