Benzalkonium chloride induces anterior chamber inflammation in previously untreated patients with ocular hypertension as measured by flare meter: a randomized clinical trial [PDF]
Anna M. Stevens +3 more
openalex +1 more source
The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu +10 more
wiley +1 more source
Hypoperfusive and hypertensive ocular manifestations in Takayasu arteritis
Jayanthi Peter1, Sarada David1, George Joseph2, Saban Horo1, Debashish Danda31Department of Ophthalmology, Schell Eye Hospital, Vellore, India; 2Department of Cardiology, Christian Medical College Hospital, Vellore, India; 3Department of Clinical ...
Jayanthi Peter +2 more
doaj
Bilateral Exudative Retinal Detachment in a Young Patient with Chronic Renal Failure
Olufunmi Adebimpe Ijeoma Otuka,1 Lisa Ifenyinwa Eweputanna,2 Nneka Chioma Okoronkwo,3 Anya Kalu1 1Ophthalmology Unit, Department of Surgery, Abia State University Teaching Hospital, Aba, Abia State, Nigeria; 2Department of Radiology, Abia State ...
Otuka OAI +3 more
doaj
Fixed-combination brinzolamide 1%/brimonidine 0.2% vs monotherapy with brinzolamide or brimonidine in patients with open-angle glaucoma or ocular hypertension: results of a pooled analysis of two phase 3 studies [PDF]
Tony Realini +3 more
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Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha +13 more
wiley +1 more source
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang +15 more
wiley +1 more source
Thomas K Mundorf1, Steven H Rauchman2, Robert D Williams3, Ricardo Notivol4, Brinzolamide/Timolol Preference Study Group51Mundorf Eye Center, Charlotte, NC, USA; 2North Valley Eye Medical Group, Mission Hills, CA, USA; 3Taustine Eye Center, Louisville ...
Thomas K Mundorf +4 more
doaj
Prevalence of glaucoma and characteristics of ocular manifestations in patients with Naevus of Ota
Aims This cross-sectional study aimed to determine the prevalence of glaucoma and associated ocular characteristics in Thai patients with Naevus of Ota, comparing those with ocular melanocytosis or oculodermal melanocytosis to those exhibiting only skin ...
Woraphong Manuskiatti +6 more
doaj +1 more source
Comparison of Newly Diagnosed Ocular Hypertension and Open-Angle Glaucoma: Ocular Variables, Risk Factors, and Disease Severity [PDF]
Yvonne M. Buys +10 more
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