Results 221 to 230 of about 680,290 (258)

The role of thrombospondin-1 in trehalose-induced autophagy and ocular hypertension in mice. [PDF]

Sci Rep
Ling CY, Choy KY, Li HL, Tse CY, Yang WY, Wong NW, Stamer WD, Do CW, Tse DY, Shan SS.   +9 more
europepmc   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Travoprost intraocular implants: pioneering a new approach in ocular hypertension management. [PDF]

Ann Med Surg (Lond)
Shahnoor S, Sohail A, Advani P, Nasheet K, Saeed I, Junaid Y, Rustam A, Ahsan M, Mustafa S, Mahmmoud Fadelallah Eljack M.   +9 more
europepmc   +1 more source

WONOEP appraisal: Biomarkers and treatment strategies beyond the synapse

Epilepsia, EarlyView.
Abstract Epilepsy is a heterogeneous neurological disorder affecting more than 70 million people worldwide, posing significant challenges for clinicians due to its complex etiology, diverse manifestations, variable treatment responses, and the inability to predict seizures or disease onset reliably.
Mirte Scheper, Zining Liu, Aristea S. Galanopoulou, Gernot Hlauschek, Benjamin Sinclair, Wai Lam Leung, Stefanie Dedeurwaerdere, Elisabeth Doran, Solomon L. Moshé, David C. Henshall, Ozlem Akman, Pablo M. Casillas‐Espinosa   +11 more
wiley   +1 more source

Therapeutic problems in ocular hypertension

Indian Journal of Ophthalmology, 1983
Sood N, Grover A, Agarwal H
doaj  

TRPV4 controls circadian and pathological ocular hypertension. [PDF]

J Physiol
Redmon SN, Lakk M, Tseng YT, Rudzitis CN, Searle JE, Ahmed F, Unser AM, Borrás T, Torrejon K, Križaj D.   +9 more
europepmc   +1 more source

Revisiting the concept that interictal implies asymptomatic: Pulse wave amplitude drops uncover autonomic responses during generalized paroxysmal fast activities

Epilepsia, EarlyView.
Abstract Objective Interictal electroencephalographic (EEG) activities are generally considered asymptomatic. Pulse wave amplitude drop (PWAD) is a marker of autonomic nervous system (ANS) reactivity linked to cardiovascular risk. Generalized paroxysmal fast activity (GPFA) is a major EEG pattern in different epileptic conditions.
Julie Lévi‐Strauss, Valerio Frazzini, Claude Adam, Isabelle Gourfinkel‐An, Sophie Dupont, Vincent Navarro, Vi‐Huong Nguyen‐Michel   +6 more
wiley   +1 more source

Mechanistic Insights into Glucocorticoid-Induced Ocular Hypertension Using Differences in Mouse Strain Responsiveness. [PDF]

Am J Pathol
Patel PD, Patel GC, Millar JC, Feris S, Curry S, Geisert EE, Clark AF.   +6 more
europepmc   +1 more source

Impact of vigabatrin on risk of relapse of infantile spasms

Epilepsia Open, EarlyView.
Abstract Objective Vigabatrin is an effective treatment for infantile epileptic spasms syndrome (IESS), but relapse remains a clinical challenge. The ideal dose and duration of treatment after response are unknown. We set out to identify treatment‐related predictors of IESS relapse after initial vigabatrin response. Methods We conducted a retrospective
Yaretson I. Carmenate, Hayoung E. Ahn, Haley R. Peters, Hiroki Nariai, Rajsekar R. Rajaraman, Shaun A. Hussain   +5 more
wiley   +1 more source

Digoxin Attenuates Ocular Hypertension and Protects Trabecular Meshwork Cells via Ferroptosis Inhibition. [PDF]

Invest Ophthalmol Vis Sci
Zhou X, Li Z, Zhang X, Xu J, Wu P, Zhu W, Ji D, Duan X.   +7 more
europepmc   +1 more source