Results 31 to 40 of about 89,340 (260)

Uveitic Ocular Hypertension and Glaucoma [PDF]

Ocular Immunology and Inflammation, 2017
Ocular hypertension (OHT) and glaucoma are common and often serious complications of uveitis.1–9 Cross-sectional clinic-based studies have suggested a prevalence of OHT among uveitis referral patie...
Emmett T. Cunningham, Manfred Zierhut
openaire   +2 more sources

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Association of Retinal Vascular Caliber and Age-Related Macular Degeneration in Patients With the Acquired Immunodeficiency Syndrome. [PDF]

, 2018
PurposeTo evaluate the relationship between retinal vascular caliber and AMD in patients with AIDS.MethodsParticipants enrolled in the Longitudinal Study of the Ocular Complications of AIDS had retinal photographs taken at enrollment.
Danis, Ronald P, Hunt, Peter W, Jabs, Douglas A, Pak, Jeong Won, Van Natta, Mark L   +4 more
core   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

Glaucomatous vertical vessel density asymmetry of the temporal raphe detected with optical coherence tomography angiography. [PDF]

, 2020
Changes in retinal vasculature and ocular circulation may play an important role in the glaucoma development and progression. We evaluated the vertical asymmetry across the temporal raphe of the deep retinal layer vessel density, using swept-source ...
Araie, Makoto, Ibuki, Hisashi, Kanno, Junji, Shinoda, Kei, Shoji, Takuhei, Weinreb, Robert N, Yoshikawa, Yuji   +6 more
core  

Efficacy of Three Different Prophylactic Treatments for Postoperative Nausea and Vomiting after Vitrectomy: A Randomized Clinical Trial [PDF]

, 2019
Postoperative nausea and vomiting (PONV) after vitreoretinal surgery may potentially be associated with severe complications, such as suprachoroidal hemorrhage.
Astuto, M., Avitabile, T., Bonfiglio, V., Boscia, F., Cagini, C., Cennamo, G., Cillino, S., Fallico, M., Fiore, T., Furino, C., Longo, A., Minardi, C., Murabito, P., Nowomiejska, K., Reibaldi, M., Rejdak, R., Rinaldi, M., Russo, A., Toro, M.   +18 more
core   +3 more sources

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Associations with photoreceptor thickness measures in the UK Biobank. [PDF]

, 2019
Spectral-domain OCT (SD-OCT) provides high resolution images enabling identification of individual retinal layers. We included 32,923 participants aged 40-69 years old from UK Biobank.
Aslam, Tariq, Balaskas, Konstantinos, Barman, Sarah A, Barrett, Jenny H, Bishop, Paul, Blows, Peter, Bunce, Catey, Carare, Roxana O, Chakravarthy, Usha, Chan, Michelle, Chua, Sharon YL, Consortium, UK Biobank Eye Vision, Crabb, David P, Cumberland, Philippa M, Day, Alexander, Desai, Parul, Dhillon, Baljean, Dick, Andrew D, Egan, Cathy, Ennis, Sarah, Foster, Paul J, Fruttiger, Marcus, Gallacher, John EJ, Garway-Heath, David F, Gibson, Jane, Gore, Dan, Guggenheim, Jeremy A, Hammond, Chris J, Hardcastle, Alison, Harding, Simon P, Hogg, Ruth E, Hysi, Pirro, Keane, Pearse A, Khaw, Sir Peng T, Khawaja, Anthony P, Lascaratos, Gerassimos, Lotery, Andrew J, Macgillivray, Tom, Mackie, Sarah, Martin, Keith, Mcgaughey, Michelle, Mcguinness, Bernadette, Mckay, Gareth J, Mckibbin, Martin, Mitry, Danny, Moore, Tony, Morgan, James E, Muthy, Zaynah A, O'Sullivan, Eoin, Owen, Chris G, Patel, Praveen J, Paterson, Euan, Peto, Tunde, Petzold, Axel, Rahi, Jugnoo S, Reisman, Charles, Rudnicka, Alicja R, Self, Jay, Sivaprasad, Sobha, Steel, David, Stratton, Irene, Strouthidis, Nicholas, Sudlow, Cathie, Tapp, Robyn, Thaung, Caroline, Thomas, Dhanes, Trucco, Emanuele, Tufail, Adnan, Vernon, Stephen A, Viswanathan, Ananth C, Vitart, Veronique, Williams, Cathy, Williams, Katie, Woodside, Jayne V, Yang, Qi, Yates, Max M, Yip, Jennifer, Zheng, Yalin   +77 more
core   +10 more sources

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

Advanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan, Jonathan James Stanley Rickard, Mark Robert Thomas, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source

Patient-reported outcomes measures and patient preferences for minimally invasive glaucoma surgical devices. [PDF]

, 2020
BackgroundMany therapeutic options are available to glaucoma patients. One recent therapeutic option is minimally invasive glaucoma surgical (MIGS) devices. It is unclear how patients view different treatments and which patient-reported outcomes would be
George Spaeth, GH Guyatt, GL Spaeth, Jimmy T. Le, Jimmy T. Le, JT Le, KL Cheung, Kuldev Singh, Malvina Eydelman, MB Eydelman, Michelle E. Tarver, NK Gale, NL Hunter, Qi N. Cui, QN Cui, Ronald D. Hays, T Weldring, Tianjing Li   +17 more
core   +1 more source