Results 241 to 250 of about 213,494 (300)
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Ocular Hypotensive Action of Labetalol
American Journal of Ophthalmology, 1979Labetalol has a unique and profound effect on the IOP of rabbits, in contrast to pure beta-adrenergic blockers which have little or no effect in this animal. Its action cannot be satisfactorily explained by simple alpha and beta-adrenergic blocking activity.
I H, Leopold, D L, Murray
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The Effect of Ocular Hypotensive Agents on Macula
Annals of Ophthalmology, 2007We evaluated the effect of long-term topical antiglaucoma drugs on the macula using the noninvasive macular visual field threshold test in 100 eyes of 75 patients with ocular hypertension or primary open-angle glaucoma. We found that topical antiglaucoma agents can alter macular sensitivity after long-term therapy and advise evaluation of the macula in
Ozturk, Faruk +2 more
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Ocular Hypotensives and Neuroprotectants in Glaucoma
2016Glaucoma is the leading cause of blindness in the world. It is an optic neuropathy disease associated with elevated intraocular pressure. Glaucoma encompass a group of various clinical presentations that share the same anatomical feature, a progressive loss of retinal ganglion cells (RGCs) superior to the age-related loss.
Dada, Tanuj +3 more
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Veterinary Clinics of North America: Small Animal Practice, 2004
The glaucomas are vision-threatening diseases that commonly result in blindness. In addition to knowledge of the at-risk breeds and predisposing factors for glaucoma as well as the clinical signs of the disease, regular IOP screening with tonometry is required to confirm glaucoma and to monitor the status of the eye.
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The glaucomas are vision-threatening diseases that commonly result in blindness. In addition to knowledge of the at-risk breeds and predisposing factors for glaucoma as well as the clinical signs of the disease, regular IOP screening with tonometry is required to confirm glaucoma and to monitor the status of the eye.
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Patient satisfaction with topical ocular hypotensives
Clinical & Experimental Ophthalmology, 2012AbstractBackground: The aim of this study is to assess patient satisfaction, convenience of use, ease of administration, side effects and treatment burden of topical ocular hypotensives.Design: Prospective, observational cohort.Participants: Two thousand five hundred and forty‐one patients with glaucoma or ocular hypertension.Methods: The Treatment
Nathan M, Kerr +5 more
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PhXA34-Induced Ocular Hypotension
Archives of Ophthalmology, 1992To the Editor. —The article by Alm and Villumsen 1 indicated that PhXA34, a congener of prostaglandin F 2α isopropyl ester (PGF 2α -IE), increased tonographic outflow facility in ocular normotensive humans by approximately one third, accounting for approximately one fourth to one third of the drug-induced intraocular pressure (IOP) decrease.
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Mechanism of the Ocular Hypotensive Action of Ketanserin
Journal of Ocular Pharmacology and Therapeutics, 1985Ketanserin has been characterized as a relatively selective antagonist for serotonin (5-HT2) receptors. However, recent evidence suggests that ketanserin can also antagonize activity at alpha 1-adrenoceptors. Topically applied ketanserin lowered intraocular pressure (IOP) in rabbits, cats, and monkeys.
F W, Chang, J A, Burke, D E, Potter
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The central ocular hypotensive effect of clonidine
Albrecht von Graefes Archiv f�r Klinische und Experimentelle Ophthalmologie, 1979Clonidine was administered into the left vertebral artery of anesthetized cats. A dose-response curve of the lowering effect on intraocular pressure (IOP) has been made and compared with the dose-response cure obtained after intravenous administration. A more pronounced decrease in IOP after the first route of administration became evident.
H C, Innemee, P A, van Zwieten
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Evaluation of Dichlorphenamide as an Ocular Hypotensive Agent
Archives of Ophthalmology, 1958Introduction The recent developments of new carbonic anhydrase inhibitors have stimulated interest in the possibility of their use as ocular hypotensive agents. The clinical and experimental value of the carbonic anhydrase inhibitor acetazolamide in lowering intraocular pressure has already been proved.
R A, SCHIMEK +3 more
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Travoprost: A potent ocular hypotensive agent
Drugs of Today, 2003Travoprost (isopropyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[alpha,alpha,alpha,trifluoro-m-tolyl)oxy]-1butenyl]cyclopentyl]-5-heptenoate) is an isopropyl ester prodrug and a high-affinity, selective FP prostaglandin- receptor full agonist. This prodrug is a synthetic prostaglandin analogue, which in appropriate cases is administered
Adel M, Al-Jazzaf +2 more
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