Results 51 to 60 of about 7,785 (171)

Toxoplasma gondii‐Derived Soluble Factors Induce G2/M Phase Accumulation and p53‐Associated Mitochondrial Apoptosis in Human Umbilical Cord Mesenchymal Stem Cells

Journal of Cellular and Molecular Medicine, Volume 30, Issue 16, August 2026.
ABSTRACT Toxoplasma gondii infection poses potential risks to stem cell‐based therapeutic applications; however, the effects of parasite‐derived soluble factors on mesenchymal stem cells remain unclear. Here, we investigated the impact of T. gondii‐derived soluble factors (Tg‐SFs) on human umbilical cord‐derived mesenchymal stem cells (hUC‐MSCs).
Wei Zhou, Tingyu Chen, Ziping Yang, Jinjing Huang, Xinyi Lai, Jie Liu, Jiaqi Chu, Juanhua Quan   +7 more
wiley   +1 more source

Histopathological diagnosis of ocular toxoplasmosis in eviscerated eyes

Human Pathology Reports
Purpose: To present two cases of ocular toxoplasmosis diagnosed by histopathological examination of eviscerated eyes. Observations: Ocular toxoplasmosis is primarily a clinical diagnosis, however atypical presentations and limitations in serological and ...
Trisha Kandiah, Rashed Alfuzaie, Guilherme Barros, Beatriz Deud, Jean Deschênes, Andrzej Kulaga, Steve Rasmussen, Rubens Belfort, Jr, Miguel Burnier, Jr   +8 more
doaj   +1 more source

Retinal tear: an unusual complication of ocular toxoplasmosis

Open Medicine, 2015
Purpose: It is aimed to report on a 16-year-old patient with acquired ocular toxoplasmosis complicated by a retinal tear. Methods: Retrospective medical chart review Results: A 16-year-old Caucasian female presented with vision loss in her right eye.
Celebi Ali Riza Cenk, Kilavuzoglu Ayse Ebru, Altiparmak Ugur Emrah, Cosar Cemile Banu, Ozkiris Abdullah   +4 more
doaj   +1 more source

Investigation of Specific IgG‐Secreting Cells in Congenital Toxoplasmosis: The TOXODIAG Study

Journal of Clinical Laboratory Analysis, Volume 40, Issue 14, July 2026.
This study addressed the difficulty of establishing a postnatal biological diagnosis of congenital toxoplasmosis, particularly in the absence of toxoplasmosis monitoring during pregnancy, as is the case in many countries. Our work presents an ELISPOT (Enzyme‐Linked Immunospot) method adapted for the detection of B lymphocytes primed to produce IgG ...
F. Migot‐Nabias, N. Beldjoudi, K. Bailly, M. Andrieu, M. Surenaud, K. Gbedande, C. Couffignal, L. Mandelbrot, H. Yera, S. Houzé, M. Dambrun, TOXODIAG Study Group, E. Akrich, O. Anselem, S. Bani, A. Benbara, J. Colombe, A.‐M. Darras, L. Dubois, N. Ettalhaoui, H. Jabbarian, J.‐M. Jouannic, S. Le Levier, S. Letrou, P. Maurice, A. Oubahim, D. Oultache, J. Sibiude, M. Valentin   +28 more
wiley   +1 more source

GLUT1 Deficiency Syndrome with Coexistent Movement Disorder and Anemia

Movement Disorders Clinical Practice, EarlyView.
Sangeetha Yoganathan, Haya S AlFaris, Anika Menetrey, Sayoni Roy Chowdhury, Lindsey Vogt, Jolynn Dickson, Karen Owusu, Pradeep Krishnan, Suvasini Sharma, Liali Aljouda, Reena Pabari, Grace Yoon, Carolina Gorodetsky   +12 more
wiley   +1 more source

Gene Panel Analysis Reveals Overlapping Genetic Causes of Inherited Cataracts and Other Ocular Phenotypes in Bulgarian Patients

Molecular Genetics &Genomic Medicine, Volume 14, Issue 7, July 2026.
We have identified 4 pathogenic/likely pathogenic changes and 2 variants of uncertain significance, 3 of which were novel. The identification of disease‐causing variants in the CRYAA, MYH9, RP2, and CLNC1 genes allowed us to establish an accurate genetic diagnosis of inherited cataract and to describe overlapping clinical phenotypes.
Kristiyana Vitanova, Kunka Kamenarova, Nevyana Veleva‐Krasteva, Kalina Mihova, Yoanna Kaneva, Reni Tzveova, Martin Georgiev, Delyan Georgiev, Ivanka Dimova, Alexander Oscar, Radka Kaneva   +10 more
wiley   +1 more source

Toxoplasmosis in the Era of Targeted Immunotherapy: A Systematic Review of Emerging Cases Linked to Biologics and Small Molecules in Autoimmune Diseases, Oncology and Transplantation

Pathogens
A systematic review of toxoplasmosis cases in patients receiving targeted immunotherapy with biologics or small molecules was performed. This systematic review searched for case reports, case series and observational studies in PubMed; last search was on
Stephanie M. Cho, Jose G. Montoya, Despina G. Contopoulos-Ioannidis   +2 more
doaj   +1 more source

Occurrence and Risk Factors of Toxoplasma gondii Infection in Tigers (Panthera tigris) in Thailand: Influence of Age and Sex

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This study investigated Toxoplasma gondii specific antibodies in 135 captive tigers across seven Thai tiger parks using latex agglutination. Results revealed a high overall positivity rate of 42.96%. Ordinal logistic regression analysis demonstrated sex and age were significant risk factors, with females (OR = 20.13) and older tigers (OR = 1.91 ...
Phirom Prompiram, Chalisa Mongkolphan, Aeknarin Saechin, Siriporn Tangsudjai, Kanaporn Poltep   +4 more
wiley   +1 more source

Treatment of ocular toxoplasmosis in pregnancy

Philippine Journal of Ophthalmology, 2004
Objectives: To describe the course of ocular toxoplasmosis during pregnancy. Methods: This is a retrospective, noncomparative case series of four pregnant women who were treated for ocular toxoplasmosis during pregnancy.
Leila I. Kump, MD, Ian Paredes, MD, C. Stephen Foster, MD, FACS   +2 more
doaj  

Simulated Microgravity Reprograms Host Cell Architecture and Mitochondrial Function, Altering Toxoplasma gondii Growth

FASEB BioAdvances, Volume 8, Issue 7, July 2026.
Simulated microgravity (SMG) induces host‐cell‐specific mitochondrial remodeling that differentially regulates T. gondii intracellular growth. Mitochondrial dysfunction with reduced ATP production is associated with impaired parasite invasion and growth in HFF, whereas mitochondrial adaptation with increased ATP production in Vero cells is associated ...
Musfika Tasnim Shirin, Takafumi Yamada, Daisuke Kondoh, Hiroki Bochimoto, Kentaro Kato   +4 more
wiley   +1 more source