Results 31 to 40 of about 59,970 (304)

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Posterior Segment Trauma

, 2016
Mechanical ocular trauma involving the posterior segment may result in damage to the choroid, vitreous body, retina, macula, and optic nerve, leading to permanent visual impairment or severe visual loss.
Smiddy, William E, William E. Smiddy
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Anterior Segment Trauma

, 2016
Mechanical ocular trauma involving the anterior segment may result in damage to the conjunctiva, cornea, limbus, anterior chamber angle, iris, lens, and ciliary body. The mechanism of trauma (closed or open, blunt, penetrating, or perforating), force and
Lee, Richard K., Sayed, Mohamed S., Richard K. Lee, Mohamed S. Sayed   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Trauma ocular contuso: análise de 240 pacientes adultos atendidos em consultório particular de Florianópolis-SC. [PDF]

, 2008
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Kriegl, Jean Philippe
core  

Traumatic Brain Injury in Admitted Patients with Ocular Trauma [PDF]

Objectives: To characterize the epidemiology of simultaneous traumatic brain injury (TBI) and ocular trauma. Materials and Methods: In this retrospective, observational study, de-identified data from patients admitted with ocular trauma and TBI was ...
Kevin Zhang, Afshin Parsikia, Catherine H. He, Joyce N. Mbekeani, Timothy Truong   +4 more
core   +1 more source

COMMON OCULAR TRAUMA

Journal of the American Medical Association, 1959
Physicians who are not ophthalmologists sometimes are obliged to treat eye injuries either because of the nature of their practice or because the situation demands immediate medical care. The minimum equipment includes some form of magnifier, a source of light, and a treatment tray, the contents of which are here listed. Chemicals splashed into the eye
openaire   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Trauma ocular na infância: estudo de 77 casos atendidos m consultório privado de Florianópolis (CS), entre 1996 e 2004. [PDF]

, 2008
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Chevarria, Francisco de Calazans
core