Results 71 to 80 of about 124,321 (238)

Clinical and demographic data and the significance of various dysfunctions and severity indicators in multiple sclerosis patients

Ukrainian Neurosurgical Journal
Introduction: Visual and oculomotor disorders are frequent manifestations of nervous system damage in multiple sclerosis. Multiple sclerosis is associated with an increased risk of falls, degeneration of sensory organization, and a possible ...
Gennadii M. Chupryna, Natalia V. Khanenko   +1 more
doaj   +1 more source

血管病相关性眼肌麻痹病因的研究进展 Study Progress of Etiology of Ophthalmoplegia Associated with Vascular Disease

Zhongguo cuzhong zazhi, 2018
眼肌麻痹是神经内科、眼科、神经眼科的常见体征。根据病变部位，血管病相关的眼肌 麻痹可分为核上型、核型、核间型、周围神经型，不同型别的眼肌麻痹有不同的病因。核上型、核型 及核间型眼肌麻痹多见于卒中，其中核型眼肌麻痹以动眼神经核受累最常见。周围神经型眼肌麻痹 病因众多，如糖尿病性眼肌麻痹、动脉瘤、颈内动脉海绵窦瘘等。糖尿病性眼肌麻痹多累及动眼神经， 瞳孔受累较轻，一般数周后开始恢复；动脉瘤和颈内动脉海绵窦瘘所致眼肌麻痹需行数字减影血管 造影（digital subraction angiography ...
李然，景筠
doaj   +1 more source

XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia [PDF]

, 2016
XRCC1 is a molecular scaffold protein that assembles multi-protein complexes involved in DNA single-strand break repair1,2. Here we show that biallelic mutations in the human XRCC1 gene are associated with ocular motor apraxia, axonal neuropathy, and ...
A Chiarugi, C Breslin, C Breslin, C Marras, C Poulton, D Pinkel, E Cappelli, Emilia Komulainen, Grace Yoon, Grazia M. S. Mancini, H Takashima, Hana Hanzlikova, J Bras, J Shen, Justin D. Wagner, Keith W. Caldecott, Kevin Staras, KW Caldecott, KW Caldecott, KW Caldecott, LE Dillehay, Limei Ju, M Tetreault, Martine Tétreault, MC Moreira, MJ Eliasson, MO Bradley, Nicolas C. Hoch, P Mali, Peter Hornyak, Peter J. McKinnon, RS Tebbs, RS Tebbs, S Katyal, SF El-Khamisy, Stephanie A. Rey, Stuart L. Rulten, William Gittens, Y Fu, Y Lee, Zhao-Qi Wang, Zhihong Zeng, ZQ Wang   +42 more
core   +2 more sources

A Case of a Sudden Onset of Diplopia Revealing Third Oculomotor Palsy Due to Midbrain Hematoma

, 2020
Case Report Spontaneous brainstem hemorrhage accounts for 5%–10% of intracerebral hemorrhage. Vascular diseases in the midbrain can cause oculomotor nerve palsy (ONP) often associated with other neurological signs.
S. Sabiry, S. Bellakhdar, H. Khattab, H. Otmani, B. Moutawakil, M. Rafai   +5 more
semanticscholar   +1 more source

Clinical, Genetic, and Imaging Characteristics of SCA27B: Insights from a Large Dutch Cohort

Movement Disorders, EarlyView.
Abstract Background Deep intronic GAA repeat expansions in intron 1 of the FGF14 gene were identified in 2023 as cause of late‐onset cerebellar ataxia. Since then, GAA‐FGF14‐related ataxia (SCA27B) has emerged as one of the most common genetic causes of late‐onset cerebellar ataxia.
Teije H. van Prooije, Maartje Pennings, Roderick P.P.W.M. Maas, Jeroen de Vries, Corien Verschuuren‐Bemelmans, Vincent Odekerken, Sirwan K.L. Darweesh, Mark Huisman, Mayke Oosterloo, Arthur Buijink, Jaron van de Wardt, Els Vanhoutte, Tsz Hang Wong, Lisette Koens, Eva de Boer, Judith van Gaalen, Martijn Beudel, Dareia S. Roos, Jorrit I. Hoff, Thimo Cornelissen, Meyke Schouten, Thatjana Gardeichik, Erica van der Looij, Christine Klein, Joanne Trinh, Erik‐Jan Kamsteeg, Bart van de Warrenburg   +26 more
wiley   +1 more source

Mydriasis as a Secondary Effect in Patients With HLA‐B27–Associated Uveitis

Medicine Advances, EarlyView.
HLA‐B27‐associated acute anterior uveitis causes significant inflammation of the iris and anterior chamber, which disrupts normal parasympathetic control and results in increased sympathetic tone leading to pupil dilation (mydriasis). This finding can sometimes resemble herpetic uveitis, making a clinical context and careful evaluation crucial for ...
Saim Mahmood Khan, Menahil Faheem Siddiqui, Syeda Areesha Shoaib, Surraiya Riaz Mahmood Khan, Jawairya Muhammad Hussain, Syeda Faiqa Batool, Hudda Amjad   +6 more
wiley   +1 more source

Diagnostic Gray Zone: Isolated Left Oculomotor Nerve Palsy in the Setting of Hyperhomocysteinemia, Sphenoid Sinusitis, and Rathke’s Cleft Cyst

International Journal of Medical Students
Rathke’s Cleft Cyst (RCC) is a benign, epithelium-lined cyst arising from remnants of Rathke’s pouch, typically located in the sellar or suprasellar region, and is a documented cause of oculomotor nerve palsy via compressive mechanisms.
Shaun Nevil, Umesh G, S Anton Charles, Sofia Mondal, Chaitra C S   +4 more
doaj   +1 more source

The life and work of professor Livery Osipovich Darkshevich (1858–1925). (to the 160th anniversary since the birth of)

Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2019
The main milestones of the life and work of L.O. Darkshevich. It is noted that the work of a professor on the study of the pathology of muscles and peripheral nerves is of great interest.
T. Sh. Morgoshiia, N. A. Syroezhin
doaj   +1 more source

Neurotoxicity [PDF]

, 2014
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust, Creeley, Feldman, Grandjean, Herken, Panzica, Parent, Pessah, Rice, Román, Spencer, Spencer, Tu, Vinken, Yasui, Zawia   +15 more
core   +2 more sources

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source