Results 71 to 80 of about 14,411 (189)

Safety and efficacy of nemolizumab for atopic dermatitis up to 2 years in open‐label extension study

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 841-855, May 2026.
This study evaluated long‐term safety and efficacy in patients with moderate‐to‐severe atopic dermatitis. Patients with and without previous nemolizumab experience received nemolizumab 30 mg Q4W plus TCS/TCI. Nemolizumab was well‐tolerated through 104 weeks with clinically meaningful improvements in disease signs and symptoms.
Matthias Augustin, Marie Tauber, Robert Sidbury, Jonathan I. Silverberg, Kim A. Papp, Diamant Thaçi, Marjolein S. De Bruin‐Weller, Adam Reich, Ketty Peris, Kirk Barber, Ryszard Galus, Andrzej Kaszuba, Matthew Zirwas, Walter K. Nahm, Gretel Trullenque, Laura Maintz, Sady Alpizar, Sang Wook Son, Vivian Laquer, Linda Stein Gold, Soo Yeon Cheong, Anna Ryzhkova, Agnes Drahos, Liliana Ulianov, Christophe Piketty   +24 more
wiley   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, Volume 13, Issue 4, Page 665-675, April 2026.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Autosomal dominant cerebellar ataxia type I: A review of the phenotypic and genotypic characteristics

Orphanet Journal of Rare Diseases, 2011
Type I autosomal dominant cerebellar ataxia (ADCA) is a type of spinocerebellar ataxia (SCA) characterized by ataxia with other neurological signs, including oculomotor disturbances, cognitive deficits, pyramidal and extrapyramidal dysfunction, bulbar ...
Fujioka Shinsuke, Whaley Nathaniel, Wszolek Zbigniew K   +2 more
doaj   +1 more source

Psychosocial interventions for improving quality of life outcomes in adults undergoing strabismus surgery (Protocol) [PDF]

, 2012
This is the protocol for a review and there is no abstract. The objectives are as follows: To investigate the effects of psychosocial interventions versus no intervention on quality of life and psychosocial outcomes in adults undergoing strabismus ...
Adamson, G., Ezra, D. G., Hancox, J., MacKenzie, K., McBain, H. B., Newman, S. P.   +5 more
core   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, Volume 13, Issue 4, Page 827-833, April 2026.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source

Posterior Reversible Encephalopathy Syndrome in a Patient with Multiple System Atrophy and Multiple Myeloma

Movement Disorders Clinical Practice, EarlyView.
Jackson Mitzner, Jenny Linnoila, Yanal Shaheen, Abby L. Olsen   +3 more
wiley   +1 more source

Anti‐GD1b Disorder Presenting as Multiple Mononeuropathies

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Isolated anti GD1b disorders are quite rare. They usually present with ophthalmoplegia, sensory ataxia, paraproteinemia, and elevated cold agglutinants. The response to immunosuppressant treatment does not seem to be very effective. We report a case of isolated mononeuropathies associated with isolated anti‐GD1b antibodies, without ataxia or ...
Kamar Eid, Rim Araoui, Ragheb Ismail, Raja Sawaya   +3 more
wiley   +1 more source

Correlation between infectivity and disease associated prion protein in the nervous system and selected edible tissues of naturally affected scrapie sheep.

PLoS ONE, 2015
The transmissible spongiform encephalopathies (TSEs) or prion diseases are a group of fatal neurodegenerative disorders characterised by the accumulation of a pathological form of a host protein known as prion protein (PrP).
Francesca Chianini, Gian Mario Cosseddu, Philip Steele, Scott Hamilton, Jeremy Hawthorn, Sílvia Síso, Yvonne Pang, Jeanie Finlayson, Samantha L Eaton, Hugh W Reid, Mark P Dagleish, Michele Angelo Di Bari, Claudia D'Agostino, Umberto Agrimi, Linda Terry, Romolo Nonno   +15 more
doaj   +1 more source

Type IV Duane Syndrome [PDF]

, 2016
Purpose To identify cases of synergistic divergence whose characteristics suggest that this entity is a form of Duane syndrome. Methods The records of all patients with a Duane syndrome diagnosis, including standardized eye position photographs,
Helveston, Eugene M., Schliesser, Joshua A., Sprunger, Derek T.   +2 more
core   +1 more source

Mesial temporal lobe epilepsy with hippocampal sclerosis: Seizure, neuropsychological, and quality of life outcomes of 100 patients treated with trans‐anterior T1 selective amygdalohippocampectomy

Epileptic Disorders, Volume 28, Issue 2, Page 389-400, April 2026.
Abstract Objective For mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE with HS), laser interstitial thermal therapy has recently been increasingly used. At our institute, however, selective amygdalohippocampectomy by a trans‐anterior T1 subpial approach (trans‐anterior T1 SAH) has been used for MTLE with HS. Here, we examined the seizure,
Naotaka Usui, Hiroshi Ogawa, Akihiko Kondo, Kazumi Matsuda, Mitsuru Hashiguchi, Taro Okumura, Yuuki Ishida, Norihiko Kawaguchi, Takashi Matsudaira, Kentaro Tokumoto, Takuji Nishida, Katsumi Imai   +11 more
wiley   +1 more source