Results 41 to 50 of about 1,571,635 (343)

Diagnostic accuracy of myocardial perfusion imaging with czt technology. Systemic review and meta-analysis of comparison with invasive coronary angiography [PDF]

, 2017
OBJECTIVES: This study sought to summarize the evidence on stress myocardial perfusion imaging (MPI) using cadmium-zinc-telluride (CZT) technology for the diagnosis of obstructive coronary artery disease (CAD). The CZT cameras are newly introduced, and
Biondi-Zoccai, Giuseppe, Frati, Giacomo, Iskandrian, Ami E., Nudi, Francesco, Peruzzi, Mariangela, Schillaci, Orazio   +5 more
core   +2 more sources

Mischievous Odds Ratios

PLoS Medicine, 2006
Pieter Reitsma and colleagues have explored—in a population of patients anticoagulated with coumarin congeners—the connection between the presence of mutant alleles of a single gene and the risk of haemorrhage [ 1]. Using as their denominator the odds for bleeding in a patient without mutant alleles, and using as their numerator the odds for ...
openaire   +4 more sources

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

L'analyse log-linéaire de tableaux de contingence et le modèle logit II : interaction et rapport de chances à propos d'un problème d'évaluation contingente

Cybergeo, 2003
In this second part of the presentation of the loglinear analysis and the logit model, the author shows, within the frame of a contingent valuation, a few examples of answers to hypotheses about relations between the acceptation to pay more for household
Estelle Kah
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Usefulness of four surrogate indexes of insulin resistance in middle-aged population in Hefei, China

Annals of Medicine, 2022
Objective Previous study have shown that lipid accumulation product (LAP), visceral adiposity index (VAI), triglyceride/high-density lipoprotein cholesterol ratio (TG/HDL-C) and triglycerides/glucose index (TyG index) could be simple clinical indicators ...
Rui Huang, Zi Cheng, Xingyi Jin, Xuemin Yu, Jinhui Yu, Yunpeng Guo, Li Zong, Jie Sheng, Xing Liu, Sufang Wang   +9 more
doaj   +1 more source

Quantifying and estimating additive measures of interaction from case-control data

, 2017
In this paper we develop a general framework for quantifying how binary risk factors jointly influence a binary outcome. Our key result is an additive expansion of odds ratios as a sum of marginal effects and interaction terms of varying order.
Alfredsson, Lars, Hedström, Anna Karin, Hössjer, Ola, Kockum, Ingrid, Lekman, Magnus, Olsson, Tomas   +5 more
core   +1 more source

Inequity in access to transplantation in the UK [PDF]

, 2020
Background and objectives Despite the presence of a universal health care system, it is unclear if there is intercenter variation in access to kidney transplantation in the United Kingdom.
Bradley, Andrew, Bradley, Clare, Draper, Heather, Dudley, Christopher, Fogarty, Damian, Forsythe, John L., HASH(0x55f513e14050), Johnson, Rachel J., Metcalfe, Wendy, Oniscu, Gabriel C., Pruthi, Rishi, Ravanan, Rommel, Robb, Matthew L., Roderick, Paul J., Tomson, Charles R. V., Watson, Christopher   +15 more
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

A Review on Logistic Regression in Medical Research

National Journal of Community Medicine, 2022
In today’s scenarios many healthcare decisions are being taken by predictive modeling and machine learning techniques. With this review, we focused on logistic regression model, a kind of predictive modeling used in machine learning, and how healthcare ...
Nihar Ranjan Panda
doaj   +1 more source