Results 121 to 130 of about 15,072 (248)

Generative models of cell dynamics: from Neural ODEs to flow matching. [PDF]

Commun Biol
Richter T, Wang W, Palma A, Theis FJ.
europepmc   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Implementing physics-informed neural networks with deep learning for differential equations. [PDF]

Front Artif Intell
Emmert-Streib F, Tripathi S, Farea A, Holzinger A.   +3 more
europepmc   +1 more source

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.
ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada, Mary P. Choules, Frances A. Brightman, Shigeru Takeshita, Shinsuke Nakao, Nobuaki Amino, Takeshi Nakayama, Masato Takeuchi, Kanji Komatsu, Fernando Ortega, Hitesh Mistry, David Orrell, Christophe Chassagnole, Peter L. Bonate   +13 more
wiley   +1 more source

Enhancing heat and mass transfer in hybrid nanofluid with gyrotactic microbes and local thermal non equlibrium effects using artificial neural network. [PDF]

Discov Nano
Aoudia M, Benabdallah F, Khan MS, Khan I, Abbas M.   +4 more
europepmc   +1 more source

Indian and African monsoons: Trajectories and interactions

Quarterly Journal of the Royal Meteorological Society, EarlyView.
The catch basin of marine air particles of the Indian monsoon is the tropical Indian ocean, whilst that of the African monsoon is the east tropical Atlantic. However, the oscillations induced by the monsoonal interactions favour particle exchange between the two basins. These transitions are abrupt in the presence of stochastic resonance. The monsoonal
Giovanni A. Dalu, Marina Baldi
wiley   +1 more source

Distributed Optimization of Finite Condition Number for Laplacian Matrix in Multi‐Agent Systems

International Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT This paper addresses the distributed optimization of the finite condition number of the Laplacian matrix in multi‐agent systems. The finite condition number, defined as the ratio of the largest to the second smallest eigenvalue of the Laplacian matrix, plays an important role in determining the convergence rate and performance of consensus ...
Yicheng Xu, Faryar Jabbari
wiley   +1 more source

Toward cardiac electrophysiology digital twins with an efficient open source scalable solver on GPU clusters. [PDF]

Sci Rep
Berg LA, Oliveira RS, Camps J, de Lima LMR, de Oliveira Campos J, Wang ZJ, Doste R, Bueno-Orovio A, Dos Santos RW, Rodriguez B.   +9 more
europepmc   +1 more source

Colloidal Quasi‐2D Cs2AgBiBr6 Double Perovskite Nanosheets: Synthesis and Application as High‐Performance Photodetectors

Small, EarlyView.
Layered quasi‐2D Cs2AgBiBr6 nanosheets, with large lateral dimensions of up to 1.4 µm, which are only a few nanometers thick, were synthesized as a result of systematic investigation of the roles of ligands and reaction temperature. The nanosheets were used to develop high‐performance photodetectors, yielding detectivity in the order of 1012 Jones with
Pannan I. Kyesmen, Eugen Klein, Brindhu Malani S, Rostyslav Lesyuk, Christian Klinke   +4 more
wiley   +1 more source

Format-Preserving Reduction of Canonical Nonlinear Models. [PDF]

Bull Math Biol
Voit EO.
europepmc   +1 more source