Results 41 to 50 of about 624,071 (226)

Novel PTCH1 mutations in patients with keratocystic odontogenic tumors screened for nevoid basal cell carcinoma (NBCC) syndrome. [PDF]

PLoS ONE, 2012
Keratocystic odontogenic tumors (KCOTs) are cystic tumors that arise sporadically or associated with nevoid basal cell carcinoma syndrome (NBCCS).
Lorenza Pastorino, Annamaria Pollio, Giovanni Pellacani, Carmelo Guarneri, Paola Ghiorzo, Caterina Longo, William Bruno, Francesca Giusti, Sara Bassoli, Giovanna Bianchi-Scarrà, Cristel Ruini, Stefania Seidenari, Aldo Tomasi, Giovanni Ponti   +13 more
doaj   +1 more source

Evaluation of Odontogenic Tumors Frequency in Biopsies Sent to Isfahan, Shiraz and Yazd Dental Schools

مجله دانشکده دندانپزشکی اصفهان, 2022
Odontogenic cysts and tumors are lesions found in the upper and lower jaw and oral soft tissue. The understanding and correct diagnosis of odontogenic tumors is essential because they can be invasive or recurrent in nature and ...
Seyed Mohammad Razavi, Nafiseh Tadayon, Seyed Hosein Tabatabaei, Zohreh Jaafari-Ashkavandi, Laleh Maleki   +4 more
doaj   +1 more source

Optimized micro‐sized cell sphere‐matrix niche co‐aggregates promote efficient oral and craniomaxillofacial bone regeneration

BMEMat, EarlyView.
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang, Shi‐Han Mu, Yi‐Han Xiao, Lu‐Fan Yang, Peng‐Fei Wang, Teng‐Fei Hu, Jun‐Xi He, Jiong‐Zhen Piao, Sha Zhang, Jin‐Yu Liu, Yi‐De He, Ying‐Ying Wu, Si‐Qi Ying, Xin‐Yue Cai, Chen‐Han Li, Zi‐Qi Zhang, Xiao Lei, Ji Chen, Jian‐Fei Liang, Yan Jin, Bing‐Dong Sui, Chao Ma, Chen‐Xi Zheng, Fang Jin   +23 more
wiley   +1 more source

Mechanical memory in aging: From adaptive sensing to pathological entrenchment

Interdisciplinary Medicine, EarlyView.
Mechanical memory in aging operates through four temporal tiers, from cytoskeletal remodeling to metabolic reprogramming. Aging disrupts this cascade through three distinct decoupling patterns: sensor degradation, conduction blockade, and execution failure, leading to irreversible pathological entrenchment across multiple organ systems.
Mingyang Huang, Xiaoyu Ma, Ruiqi Gao, Qichen Miao, Guoqing Wang, Ziyuan Liu, Kun Wang, Ming Luo   +7 more
wiley   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Patho-radiological concept of ectodermal odontogenic tumors

, 1986
The three epithelial odontogenic tumors have characteristic hisopathologic and x-ray features as well as clinical behavior. Althought the differential diagnosis of epithelial odontogenic tumors could be done without confusion, the roentgenographic ...
Lim C.Y.
core   +1 more source

Odontogenic tumors in Western India (Gujarat): analysis of 209 cases [PDF]

, 2011
Objective: Odontogenic tumors show a distinct geographic variation. In 2005 a new WHO classification was published which included odontogenic keratocyst as one of the odontogenic tumors, renaming it as a keratocystic odontogenic tumor.
D. Jani, J. Chawda, Gill, Sharanjeet, Jani, Dhaval, Chawda, Jyoti, S. Gill   +5 more
core   +1 more source

Evolution of Bacterial Yield and Antimicrobial Resistance in Chronic Rhinosinusitis Patients in a Dedicated Sinus Centre

Clinical Otolaryngology, EarlyView.
ABSTRACT Background Antibiotics are frequently prescribed for acute exacerbations of chronic rhinosinusitis (CRS). However, antimicrobial resistance presents a challenge for the ongoing and future management of CRS patients. Objective This study aims to examine the current and past microbiological yield and antimicrobial resistance profile in a ...
Timoleon Siempis, Zhu Yeap, Shifa Ali, Carl M. Philpott   +3 more
wiley   +1 more source

Targeting CKIP‐1 for Disease Therapy: Cellular Functions, Molecular Networks, and Clinical Potential

Cell Proliferation, EarlyView.
CKIP‐1, as a scaffold protein with special structural domains, treats related diseases through multiple emerging targeted technologies.
Xin Huang, Shijie Lv, Lejia Li, Jirong Xie, Zhengguo Cao   +4 more
wiley   +1 more source

Novel and emerging skin carcinomas and adnexal tumours

Histopathology, EarlyView.
The present review aims to provide an overview of the main emerging skin epithelial tumours, with particular emphasis on salivary gland analogue sweat gland tumours and poorly differentiated carcinomas. Epidermal and adnexal tumours of the skin constitute a complex and heterogeneous group of neoplasms, with distinct morphology and behaviour.
Thibault Kervarrec, Maxime Battistella, Nicolas Macagno   +2 more
wiley   +1 more source