Results 61 to 70 of about 9,836 (239)

Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity

Advanced Science, EarlyView.
In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin, Lu‐Jun Zhou, Hui‐Lin Ye, Ting Liu, Bo‐Yan Chen, Xue‐Bing Bai, Jun Zhang, Lan Bai, Lin‐Juan Du, Yuan Liu, Yong‐Li Wang, Hong Zhu, Yu‐Lin Li, Shuo Xu, Xiao‐Qian Meng, Guo‐Cai Tian, Yan Liu, Wu‐Chang Zhang, Ya‐Qin Zhu, Sheng‐Zhong Duan   +19 more
wiley   +1 more source

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

Advanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman, Carla Alvarez Rivas, Aashish Srivastava, Nora Marek, Kamal Mustafa, Alpdogan Kantarci   +5 more
wiley   +1 more source

Sensory Nerve‐Derived CGRP Controls Osteoclastogenesis by Limiting Macrophage Bioenergetics in Bone Repair

Advanced Science, EarlyView.
Sensory nerves help bones heal. This study shows that the neuropeptide CGRP, released from sensory nerves, slows down macrophage energy production, preventing excessive bone breakdown. By revealing this nerve–immune–metabolism connection, the work provides new insight into how the body balances bone repair and opens doors to targeted treatments ...
Jiaying Liu, Ting Zhang, Yuqing Mu, Lili Li, Ju Jin, Kevin J Dudley, Wendong Gao, Donglin Cai, Fuhua Yan, Lan Xiao, Yin Xiao   +10 more
wiley   +1 more source

A BioLiving Periosteum Evokes Centripetal Regeneration in Challenging Bone Defects

Advanced Science, EarlyView.
Large bone defects often suffer from insufficient central healing. This study engineers a BioLiving periosteum that mimics the native structure. It sequentially delivers remote chemical cues and contact physical cues in a signaling‐relay manner, effectively recruiting and guiding endogenous cells toward the defect center.
Yang Shi, Nian Liu, Jingyi Gu, Yinling Wang, Weiye Wang, Zhiwei Ke, Mingjun Xie, Wenjing Jin, Weicheng Kong, Jue Shi, Hui Pan, Yong He, Zhijian Xie   +12 more
wiley   +1 more source

Non-Metric Dental Traits in Human Skeletal Remains from Transcaucasian Populations: Phylogenetic and Diachronic Evidence

Anthropological Review, 2014
The aim of the study is the assessment of biological distance between populations from Transcaucasia on the basis of the frequency of dental morphological traits.
Khudaverdyan Anahit Yu.
doaj   +1 more source

Craniology and odontology of the Early Medieval population alongside the Tobol river, based on Ustyug-1 burial ground

Вестник археологии, антропологии и этнографии, 2016
The article presents the results of craniological and odontological research based on a group of Ustyug-1 burial ground. The goal of the research is to determine genesis of the Bakal population from the Tobol river region of the Great Migration time ...
Poshekhonova O.E., Zubova A.V., Sleptsova A.V.   +2 more
doaj   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

Advanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin, Supawadee Jariyasakulroj, Yang Shu, Jingyi Chen, Qing Chang, Pao‐Fen Ko, Yuyueyang Qiu, Feixiang Chen, David Ahn, Zhen Zhao, Jian‐Fu Chen   +10 more
wiley   +1 more source

Profilaxis antimicrobiana en Estomatología y su aplicación en periodoncia Antimicrobial prophylaxis in Dentistry and its applicatoin in Periodontics

Revista Cubana de Estomatología, 2006
Se analiza la información publicada en los últimos años referente al uso apropiado de la profilaxis antimicrobiana (PA) en la práctica estomatológica en general y en procedimientos periodontales en particular.
Susana Aurora Macín-Cabrera, Mariano Sanz Alonso, Carlos Tomás Quirino-Barreda   +2 more
doaj  

Dysregulation of Oral Microbial Eicosapentaenoic Acid Induced by Chronic Restraint Stress Exacerbates Periodontitis via M1 Macrophage Polarization

Advanced Science, EarlyView.
ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo, Fangzhi Lou, Peiran Yang, Yu Zhang, Li Yan, Yunmei Dong, Bing Yang, Haiyang Wang, Yiyun Liu, Juncai Pu, Richard D. Cannon, Peng Xie, Ping Ji, Xin Jin   +13 more
wiley   +1 more source

Can Noise in Dental Clinic Produce Hearing Loss?

International Archives of Otorhinolaryngology, 2011
Introduction: The sensorial hearing loss and irreversible noise induced is the major evitable occupational cause of hearing loss worldwide. The dentists are health professionals exposed to noises from equipment in their clinics and may suffer hearing ...
Lourenço, Edmir Américo, Berto, Janaína Medina da Rocha, Duarte, Sávio Butignolli, Greco, João Paulo Martins   +3 more
doaj