Results 141 to 150 of about 82,907,714 (218)
Multivalent RNA‐Cleaving Agents on a Cubic Octameric Silsesquioxane Core
RNA‐cleaving agents on a cubic octameric silsesquioxane core were synthesized and characterized. Several catalytic systems of these structures were screened using hexaribonucleotide models. The best systems were then further used to study their catalytic efficiency in cleaving a HER2 mRNA model sequence. The induced cleavage sites were also determined.
Hanni Haapsaari, Iris Tuomi, Pasi Virta
wiley +1 more source
We report a systematic study of β‐ketonitrile–modified Prodan‐type solvatochromic fluorophores. The β‐ketonitrile substitution induces marked bathochromic shifts in absorption and emission and significantly enhances fluorescence quantum yields in nonpolar solvents.
Hiroaki Asakawa +3 more
wiley +1 more source
From Anti‐Populist Mobilisation to Centripetal Polarisation: The Czech Elections of 2025
JCMS: Journal of Common Market Studies, EarlyView.
Petra Guasti, Vlastimil Havlík
wiley +1 more source
TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu +12 more
wiley +1 more source
ABSTRACT Given the widespread reliance on insulin among diabetic patients, ensuring its stability is an essential task not only for preserving its therapeutic efficacy but also for safeguarding patient health and safety. In addition, insulin storage practices were frequently misunderstood that may compromise drug potency.
Majdi Ben Messaoud +7 more
wiley +1 more source
¿Están listos para sumergirse en el fascinante mundo de la sostenibilidad? No se pierdan nuestro próximo episodio del Podcast Planeta Sostenible; una alianza de Pacto Global Red Colombia y la Universidad del Rosario. En esta entrega, conversaremos con la
Duarte, Nelson, Gómez, Ángela María
core
Ten new compounds (9 esters, 1 alkaloid) were isolated from the flowers of Trollius chinensis Bunge, and all isolated compounds were evaluated in vitro for cytotoxicity against HeLa, HepG2, HCT 116 cells, and NO inhibition in RAW 264.7 macrophages, enriching structural diversity and providing a chemical basis for further study. . ABSTRACT In this study,
Mei‐Li Guo +6 more
wiley +1 more source
A new phenolic glycoside, cotinusin A, was isolated from the heartwood of Cotinus coggygria together with seven known compounds. Cotinusin A attenuates glutamate‑induced oxidative injury in HT22 cells (EC50 = 3.852 µM) and suppresses TNF‑α‑induced NF‑κB activation in a 293T luciferase reporter assay.
Caiwen Meng +7 more
wiley +1 more source
Reducción de las desigualdades (ODS 10)
Grado en Administración y Dirección de Empresas con Mención en ...
openaire +3 more sources
Formation of H2 and O2 directly from water by Synechocystis with photosystem II. Under anaerobic conditions, a fraction of the photosynthetically derived electrons can be directed toward H2 evolution. Pseudomonas serves as the primary O2 sink by consuming O2 through citrate supported respiration. This interaction maintains anaerobic conditions required
Kang Lyu +4 more
wiley +1 more source

