Results 91 to 100 of about 51,682 (219)

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, Volume 13, Issue 10, Page 2036-2045, October 2026.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Comparing the Outcomes of Stapled Transanal Rectal Resection, Delorme Operation and Electrotherapy Methods Used for the Treatment of Obstructive Defecation Syndrome

Iranian Journal of Medical Sciences, 2014
Background: Pathophysiology and treatment of obstructive defecation syndrome (ODS) remains to be defined clearly. Rectal hidden intussusceptions and voluminous hemorrhoids may be the cause.
Neda Mirabi, Mohammad Fazlani, Reza Raisee   +2 more
doaj  

Colombiains A–C, Three New Alkaloids From the Soft Coral‐Derived Fungus Cladosporium colombiae CSGL 10M10

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Three new alkaloids, colombiains A–C (1–3), together with eight known ones (4–11) were isolated from the soft coral‐derived fungus Cladosporium colombiae CSGL 10M10. Compounds 6 and 11 exhibited significant cardioprotective activity against OGD/R‐induced injury in H9c2 cardiomyocytes at 10 µM.
Jing Xie, Bing‐Bing Liu, Yang‐Ying Zheng, Jun‐Feng Huan, Xiao‐Yu Tian, Xiu‐Ping Lin, Hui‐Mei Xie, Yuan‐Yuan Cheng, Cui‐Xian Zhang   +8 more
wiley   +1 more source

A One-Year Retrospective Observational Study of an Occupational Medicine Outpatient Clinic in a City Hospital

Annals of Global Health
Background: Occupational diseases (ODs) remain a major public health concern. Despite advances in occupational health (OH), many workers remain at risk due to insufficient preventive measures and limited access to specialized care.
Yusuf Samir Hasanli
doaj   +1 more source

Nicotinamide and Sodium Butyrate Double the Pool of Treatment‐Exclusive Metabolites in the Endophytic Fungus Curvularia sp. G6‐32

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Epigenetic modulators nicotinamide and sodium butyrate reshape the chemical landscape of the endophytic fungus Curvularia sp. G6‐32. Combining the OSMAC strategy with UHPLC‐MS/MS metabolomics and molecular networking reveals a more than twofold rise in treatment‐exclusive metabolites, including diketopiperazines and potentially bioactive natural ...
Guilherme Edison Almeida Pega, Laís Stella Perassolli Nicchio, Andressa Domingos Polli, Francielli Alana Pereira Valeze, Évelin Lemos de Oliveira, Eduardo Cesar Meurer, Débora Cristina Baldoqui, João Lúcio Azevedo, Julio Cesar Polonio   +8 more
wiley   +1 more source

Production of Bixin‐Rich Extracts From Annatto Seeds via Ethanol–Water Extraction Integrated With Ultrafiltration Technology

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ethanol–water extraction followed by 5 kDa ultrafiltration yields a bixin‐rich annatto extract with 97.9% bixin rejection, 94.2% recovery in the retentate, and an enrichment factor of 1.29. Fouling analysis indicates an important contribution from cake formation, highlighting the role of membrane–solute interactions in the selective concentration of ...
Karolyna B. Miguel, Vicelma Luiz Cardoso, Miria Hespanhol Miranda Reis   +2 more
wiley   +1 more source

Actinomycin Analogs From Streptomyces polyantibioticus S4D258: Structural Elucidation and Antiproliferative Activity Against Triple‐Negative Breast Cancer

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Fifteen new actinomycin analogs, named actinomycins H1–H15, are identified from S. polyantibioticus S4D258. Actinomycins H7–H15 are truncated actinomycin analogs. Actinomycins H1–H6 and H9 exhibit significant antiproliferative activities against both MDA‐MB‐231 and 4T1 TNBC cells.
He Pang, Xiao‐Min Huang, Usama Ramadan Abdelmohsen, Li Shen, Jun Wu   +4 more
wiley   +1 more source

Mannosylxylarinols A and B, Two New 3,4‐Seco‐ergostane‐type Steroidal Saponins From the Fungus Xylaria necrophora SZSS1‐2‐2

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Two new 3,4‐seco‐ergostane saponins (1–2) and four known compounds were isolated from Xylaria necrophora. Structures were elucidated via spectroscopy, ECD, and computational NMR. Compound 5 selectively inhibited BV2 microglial cells (IC50 = 17.10 µM), while all compounds showed no antimicrobial activity against tested microorganisms. ABSTRACT Two new 3,
Qian Luo, Yu Yang, Rui Xu, Xue Zhao, Hui‐Fang Tan, Yu‐Ying Wei, Er‐Wei Li, Li‐Xia Chen, You‐Zhi Zhang, Chang‐Wei Li   +9 more
wiley   +1 more source

UHPLC/MS‐MS Profiling, Antioxidant and Antimicrobial Properties of Atriplex halimus L. and Marrubium deserti De Noé Extracts: In Vitro and In Silico

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
This study investigates the phytochemical profile and biological potential of Atriplex halimus L. and Marrubium deserti De Noé extracts. Polyphenolic constituents are identified using UHPLC‐MS/MS analysis, complemented by TPC and TFC evaluations. Antioxidant activities are determined via DPPH, ABTS, and FRAP assays, while antimicrobial efficacy is ...
Nacira Siad, Chahrazed Hamia, Amar Djeridane, Mohamed Benalia, Reguia Mahfoudi, Hicham Bouakkaz, Mustafa Abdullah Yilmaz, Oguz Cakir, Abbas Tarhan, Mohamed Yousfi   +9 more
wiley   +1 more source

Bioactive Compounds and Cytotoxicity of Seed and Leaf Oils of Moringa oleifera

eFood, Volume 7, Issue 5, October 2026.
Among the practical applications of the oils described in this study, their use as an ingredient in food stands out, as well as the potential for developing bioactive materials for packaging, conferring antioxidant and antimicrobial properties. Seed and leaf oils from Moringa oleifera exhibit functional properties of industrial interest and bioactive ...
Emanuela de Lima Viana, Julia da Costa Santos, Ana Caroline de Medeiros Dantas, David Henrique Xavier Barbosa, Matheus de Freitas Fernandes Pedrosa, Pablo Felipe Ferreira Farias, Susana Margarida Gomes Moreira, Patrícia Prado Augusto, Patricia Santos Lopes, Ana Paula Barreto Gomes, Rui de Oliveira Macedo, Francisco Canindé de Sousa Júnior, Cristiane Fernandes de Assis   +12 more
wiley   +1 more source