Results 61 to 70 of about 114,901,315 (309)
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao +5 more
wiley +1 more source
O presente estudo tem como finalidade analisar a interface entre o Objetivo de Desenvolvimento Sustentável 3 (ODS 3) da Agenda 2030 e a formulação jurídica da Política Pública de Saúde. O problema que norteia a pesquisa é identificar as diretrizes do ODS
Janriê Rodrigues Reck, Joice Schroer
doaj +1 more source
Since oxide dispersion-strengthened (ODS) FeCrAl-based alloys have sufficient creep strength and good oxidation resistance at the very high temperatures of interest for the primary heat exchanger in advanced, closed-cycle gas turbine systems, they ...
Wright, I. G. +2 more
core +1 more source
Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song +7 more
wiley +1 more source
The Open Discovery Space (ODS) project was conceived to introduce innovative resource-based teaching and learning practices in European schools, to promote the creation of communities between European school members and to boost the demand for open ...
Sonia PEINADO +13 more
doaj +1 more source
Nostvum Scelus (Ode I, 3 d'Horace)
info:eu-repo/semantics ...
openaire +3 more sources
Emprendedores y ODS: compromisos y cooperación
Una segunda parte sobre Emprendedores en Acción y cómo aportar a los #ODS, junto a: - Víctor Hugo Malagón, Presidente del Foro de Presidentes - Fundador de #MACA Conduce: Ángela Gómez y Angélica Sánchez - Mauricio López, Director Ejecutivo de Pacto ...
Gómez Duque, Ángela María +1 more
core
Modular zinc finger (ZF) metalloproteins function as programmable biomolecular scaffolds that modulate pathogenic amyloid assembly. Through direct protein–protein interactions, ZF arrays alter amyloid phase behavior and redirect β‐sheet fibrillization toward nontoxic aggregates.
Seongmin Park +16 more
wiley +1 more source
BACKGROUND: Recently, the Obstructed Defecation Syndrome score (ODS score) was developed and validated by Renzi to assess clinical staging and to allow evaluation and comparison of the efficacy of treatment of this disorder.
Ana Celia CAETANO +3 more
doaj +1 more source
AI‐based tools enable rapid characterization of bacterial ultrastructure in low‐dose cryogenic transmission electron microscopy. The envelope thickness tool quantifies membrane thickness and anisotropy. The flagella module analyzes filament morphology and detects cell‐flagella contacts.
Sita Sirisha Madugula +10 more
wiley +1 more source

