Results 31 to 40 of about 62,032 (234)

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

Advanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu, Huan Liu, Songyin Zhao, Lei Qin, Jiarui Li, Jun Wang, Zixuan Dai, Jie Gu, Yan Xu, Feiran Li, Yao Nie   +10 more
wiley   +1 more source

Inversión pública en salud en Ecuador: cumplimiento del ODS 3 durante el período 2017-2023

Revista Angolana de Ciências
Actualmente, la inversión pública en salud representa un elemento clave para asegurar el bienestar de la población y fomentar el desarrollo sostenible de los países.
Allison Maryori Rubio Escalante, Fabiana Mayerli Morocho Vásquez, Carlos Joel Viteri Escobar, Luis Alberto Feijoó Pogo   +3 more
doaj   +1 more source

Measurement of aerosol optical depth and sub-visual cloud detection using the optical depth sensor (ODS) [PDF]

Atmospheric Measurement Techniques, 2016
A small and sophisticated optical depth sensor (ODS) has been designed to work in the atmosphere of Mars. The instrument measures alternatively the diffuse radiation from the sky and the attenuated direct radiation from the Sun on the surface.
D. Toledo, P. Rannou, J.-P. Pommereau, A. Sarkissian, T. Foujols   +4 more
doaj   +1 more source

Automated Bacterial Identification and Morphological Feature Analysis in Low‐Dose Cryo‐EM Using YOLOv11

Advanced Intelligent Discovery, EarlyView.
AI‐based tools enable rapid characterization of bacterial ultrastructure in low‐dose cryogenic transmission electron microscopy. The envelope thickness tool quantifies membrane thickness and anisotropy. The flagella module analyzes filament morphology and detects cell‐flagella contacts.
Sita Sirisha Madugula, Lynnicia N. Massenburg, Spenser R. Brown, Amber N. Bible, Chanda R. Harris, Lance X. Zhang, Kiara Parker, Scott T. Retterer, Jennifer L. Morrell‐Falvey, Rama K. Vasudevan, Alexis N. Williams   +10 more
wiley   +1 more source

Comportamiento y desigualdades sociales en indicadores priorizados del Objetivo de Desarrollo Sostenible 3 en Bolivia

Revista Panamericana de Salud Pública, 2020
Objetivo. Describir el comportamiento y las desigualdades sociales en indicadores priorizados del Objetivo de Desarrollo Sostenible 3 (ODS-3) entre subpoblaciones y departamentos de Bolivia. Métodos.
Max Francisco Enríquez Nava, Adhemar David Esquivel Velásquez, Mabel Patón Sanjines, Bertha Cecilia Pooley Ayarza, René Alarcón, Rosalinda Hernández Muñoz, Antonio Sanhueza   +6 more
doaj   +1 more source

The Role of IgM Anti‐acetylated Protein Antibodies and B Cells in the Origin of Antimodified Protein Autoimmunity in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA). In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role ...
Aegli Athanasiadou, Sanne Kroos, Renee van de Wetering, Rian Schopmeijer, Carin van der Keur, Michael Eikmans, Caroline Meijer, Solbritt Rantapää‐Dahlqvist, René E. M. Toes, Linda M. Slot, Diane van der Woude   +10 more
wiley   +1 more source

A formulação jurídica da política pública de saúde sob a perspectiva da agenda 2030 e o desenvolvimento sustentável

Revista de Direito Econômico e Socioambiental
O presente estudo tem como finalidade analisar a interface entre o Objetivo de Desenvolvimento Sustentável 3 (ODS 3) da Agenda 2030 e a formulação jurídica da Política Pública de Saúde. O problema que norteia a pesquisa é identificar as diretrizes do ODS
Janriê Rodrigues Reck, Joice Schroer
doaj   +1 more source

New occupational diseases legislation rules – Functioning evaluation

Medycyna Pracy, 2014
Background: On 3 July 2009, new law pertaining to occupational diseases (ODs) became effective in Poland. The article presents opinions of the representatives of the 1st degree ODs certification entities and sanitary inspectorates on the changes in OD ...
Marcin Rybacki, Ewa Wągrowska-Koski, Sylwia Świderska-Kiełbik, Jolanta Walusiak-Skorupa   +3 more
doaj   +1 more source

Decarbonization Boundary Choices and the Effectiveness of Stakeholder Engagement in Voluntary Climate Action Commitments: Evidence From Emerging Economies

Business Strategy and the Environment, EarlyView.
ABSTRACT This study examines how stakeholder engagement, conceptualized as a boundary‐spanning organizational capability, interacts with firms' decarbonization strategies, in relation to climate action commitments (CACs) in voluntary initiatives.
David Tobón Orozco, Jose Pla‐Barber
wiley   +1 more source

RENZI SCORE FOR OBSTRUCTED DEFECATION SYNDROME - VALIDATION OF THE PORTUGUESE VERSION ACCORDING TO THE COSMIN CHECKLIST

Arquivos de Gastroenterologia
BACKGROUND: Recently, the Obstructed Defecation Syndrome score (ODS score) was developed and validated by Renzi to assess clinical staging and to allow evaluation and comparison of the efficacy of treatment of this disorder.
Ana Celia CAETANO, Sara DIAS, André SANTA-CRUZ, Carla ROLANDA   +3 more
doaj   +1 more source