Results 111 to 120 of about 60,839 (241)

Compassion fatigue: a challenge to comprehensive health care and SDG 3 under the 2030 Agenda. [PDF]

open access: yesRev Bras Enferm
Pereira MM   +4 more
europepmc   +1 more source

Colombiains A–C, Three New Alkaloids From the Soft Coral‐Derived Fungus Cladosporium colombiae CSGL 10M10

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Three new alkaloids, colombiains A–C (1–3), together with eight known ones (4–11) were isolated from the soft coral‐derived fungus Cladosporium colombiae CSGL 10M10. Compounds 6 and 11 exhibited significant cardioprotective activity against OGD/R‐induced injury in H9c2 cardiomyocytes at 10 µM.
Jing Xie   +8 more
wiley   +1 more source

Nicotinamide and Sodium Butyrate Double the Pool of Treatment‐Exclusive Metabolites in the Endophytic Fungus Curvularia sp. G6‐32

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Epigenetic modulators nicotinamide and sodium butyrate reshape the chemical landscape of the endophytic fungus Curvularia sp. G6‐32. Combining the OSMAC strategy with UHPLC‐MS/MS metabolomics and molecular networking reveals a more than twofold rise in treatment‐exclusive metabolites, including diketopiperazines and potentially bioactive natural ...
Guilherme Edison Almeida Pega   +8 more
wiley   +1 more source

Production of Bixin‐Rich Extracts From Annatto Seeds via Ethanol–Water Extraction Integrated With Ultrafiltration Technology

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ethanol–water extraction followed by 5 kDa ultrafiltration yields a bixin‐rich annatto extract with 97.9% bixin rejection, 94.2% recovery in the retentate, and an enrichment factor of 1.29. Fouling analysis indicates an important contribution from cake formation, highlighting the role of membrane–solute interactions in the selective concentration of ...
Karolyna B. Miguel   +2 more
wiley   +1 more source

Actinomycin Analogs From Streptomyces polyantibioticus S4D258: Structural Elucidation and Antiproliferative Activity Against Triple‐Negative Breast Cancer

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Fifteen new actinomycin analogs, named actinomycins H1–H15, are identified from S. polyantibioticus S4D258. Actinomycins H7–H15 are truncated actinomycin analogs. Actinomycins H1–H6 and H9 exhibit significant antiproliferative activities against both MDA‐MB‐231 and 4T1 TNBC cells.
He Pang   +4 more
wiley   +1 more source

Mannosylxylarinols A and B, Two New 3,4‐Seco‐ergostane‐type Steroidal Saponins From the Fungus Xylaria necrophora SZSS1‐2‐2

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Two new 3,4‐seco‐ergostane saponins (1–2) and four known compounds were isolated from Xylaria necrophora. Structures were elucidated via spectroscopy, ECD, and computational NMR. Compound 5 selectively inhibited BV2 microglial cells (IC50 = 17.10 µM), while all compounds showed no antimicrobial activity against tested microorganisms. ABSTRACT Two new 3,
Qian Luo   +9 more
wiley   +1 more source

Cytotoxic Dihydroagarofuran Sesquiterpenoids Isolated From the Roots of Tripterygium wilfordii

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ten undescribed dihydro‐β‐agarofuran derivatives were isolated from the roots of Tripterygium wilfordii. Their structures, including absolute configurations were elucidated by NMR, CD exciton chirality, ECD calculation, and single‐crystal x‐ray diffraction.
Ya‐Lin Hu   +7 more
wiley   +1 more source

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