Results 131 to 140 of about 12,854,097 (265)
ABSTRACT Deoxyuridine (dUrd) is often misincorporated into genomic DNA in cancer patients receiving antimetabolite chemotherapy. This activates base excision repair and recruits ataxia telangiectasia‐mutated and Rad3‐related (ATR), which coordinates DNA repair with nucleotide metabolism by facilitating ribonucleotide reductase (RNR) activity ...
Joshua J. Deppas +5 more
wiley +1 more source
Bioactive Compounds and Cytotoxicity of Seed and Leaf Oils of Moringa oleifera
Among the practical applications of the oils described in this study, their use as an ingredient in food stands out, as well as the potential for developing bioactive materials for packaging, conferring antioxidant and antimicrobial properties. Seed and leaf oils from Moringa oleifera exhibit functional properties of industrial interest and bioactive ...
Emanuela de Lima Viana +12 more
wiley +1 more source
Assessment of Monomer Release From Resin Composites Following the Use of Various Modeling Liquids
ABSTRACT Objectives The chemical composition of resin composites and the use of modeling liquids may influence the release of residual monomer, potentially impacting biocompatibility. This in vitro study evaluated the effect of different modeling liquids on the elution of monomers from two resin composites.
Dorukcan Yıldırım +3 more
wiley +1 more source
¿Están listos para sumergirse en el fascinante mundo de la sostenibilidad? No se pierdan nuestro próximo episodio del Podcast Planeta Sostenible; una alianza de Pacto Global Red Colombia y la Universidad del Rosario. En esta entrega, conversaremos con la
Duarte, Nelson, Gómez, Ángela María
core +1 more source
METTL18 is Required for Developmental, Metabolic, and Endocrine Regulation of Mammalian Growth
METTL18 is essential for histidine Nτ‐methylation of proteins, normal embryonic development, iron and lipid metabolism, and hormone signaling pathways that support postnatal growth in mice. The main points of this study are as follows: First, mouse METTL18 catalyzes histidine Nτ‐methylation. Next, Mettl18 KO embryos are significantly smaller than their
Fumiya Kasai +16 more
wiley +1 more source
Abstract High temperatures lead to a significant drop in rice (Oryza sativa L.) productivity worldwide, especially during the reproductive stage. This research was piloted to evaluate 10 promising rice cultivars for their ability to withstand high‐temperature stress (HS) during the reproductive phase and to assess the impact on physiology and yield ...
Summiya Faisal +9 more
wiley +1 more source
Five new iridoids, viburetins D–H, featuring dioxatricyclodecane and ring‑opened monocyclic skeletons, are isolated from the leaves of Viburnum macrocephalum f. macrocephalum, enriching the chemical diversity of Viburnum. Preliminary DPPH and ABTS assays reveal varying degrees of radical scavenging activity.
Ya‐Jiao Chen +4 more
wiley +1 more source
Two new cadinane‑type sesquiterpenes, viburetones A and B, were isolated from Viburnum macrocephalum flowers, marking the first cadinane skeletons in this genus. Viburetone A showed dual α‑amylase and α‑glucosidase inhibition comparable to acarbose, and docking clarified its binding.
Ya‐Jiao Chen +5 more
wiley +1 more source
Phenolic profile and bioactivity of Lygeum spartum L. ABSTRACT The phenolic composition of roots and leaves of Lygeum spartum L., a Mediterranean Poaceae species, was analyzed by HPLC–DAD, revealing an organ‐specific distribution of phenolic compounds, with ferulic acid identified as the predominant phenolic compound in the methanolic leaf extract (4 ...
Zohra Arabi +9 more
wiley +1 more source
Educação Digital: o acesso digital para o Objetivo de Desenvolvimento Sustentável 4 (ODS 4) [PDF]
A presente pesquisa tem por tema o acesso digital como instrumento emancipador da sustentabilidade e da educação, tendo em vista que a educação inclusiva, equitativa e de qualidade foi fixada como objetivo autônomo no âmbito da Agenda 2030.
Leviski, Daiane Schneider +1 more
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