Results 101 to 110 of about 61,661 (214)

Optimized SPE‐HPLC‐FLD Method for the Simultaneous Determination of Olaparib, Propranolol, and Furosemide in Human Urine

Biomedical Chromatography, Volume 40, Issue 8, August 2026.
ABSTRACT Olaparib belongs to the PARP inhibitors and is widely used as an anticancer drug. Due to frequent side effects, it is usually co‐administered with an antihypertensive, such as propranolol and/or an antidiuretic, such as furosemide. In this study, a highly sensitive HPLC‐FLD method was developed for the simultaneous determination of the three ...
Georgios Kamaris, Antonia Kalagia, Catherine K. Markopoulou   +2 more
wiley   +1 more source

A relação entre interdisciplinaridade e CTS: um olhar sobre as teses e dissertações brasileiras na área de ensino

Indagatio Didactica
O modo fragmentado como o conhecimento científico é ensinado aos estudantes vem criando barreiras à compreensão crítica da sociedade em que estão inseridos.
Bárbara Mulè Gonçalves, Taís Conceição dos Santos, Alvaro Chrispino   +2 more
doaj   +1 more source

Pomological and Biochemical Characterization of Autochthonous Grape Varieties Grown in Türkiye

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Eighteen autochthonous grape genotypes cultivated in Eastern Anatolia (Muş, Türkiye) were comprehensively evaluated for pomological traits, phenolic composition, vitamin C content, and antioxidant capacity. Multivariate analyses (PCA, hierarchical clustering, and correlation) revealed pronounced genotype‐dependent variation and clear trait‐based ...
Yakup Karasu, Adnan Dogan, Semih Aykut, Burhan Ozturk, Erdal Aglar   +4 more
wiley   +1 more source

Behavioral responses of black bears to human presence and infrastructure in Yosemite National Park

The Journal of Wildlife Management, Volume 90, Issue 6, August 2026.
Using GPS collar data from black bears in Yosemite National Park, we examined how bear spatiotemporal activity in relation to human development shifted during the COVID‐19 park closure in 2020. In the absence of visitors, bears maintained consistent landscape‐scale space use but altered fine‐scale spatial and temporal behaviors.
Jennifer R. Green, Caitlin Lee‐Roney, Kathleen Patrick, Rachel Mazur, Robert Lester, Erin Degutis, Ryan Leahy, Tal Avgar, Naomi B. Schwartz, Kaitlyn M. Gaynor   +9 more
wiley   +1 more source

Development of a Quantitative Method to Assess Dental Students' Manual Dexterity in Tooth Cavity Preparation

European Journal of Dental Education, Volume 30, Issue 3, Page 1098-1105, August 2026.
ABSTRACT Purpose This study aims to develop a novel method for objectively assessing dental students' manual dexterity in tooth cavity preparation using 3D technology. Materials and Methods An artificial tooth model compatible with traditional dental simulators was created using 3D scanning and printing technology.
Jong‐Ki Lee, Jongok Lee, Jeong‐Kil Park, Sung‐Ae Son, Hyoung Seok Shin, Jae‐Hoon Kim   +5 more
wiley   +1 more source

Rice EMF3 Alleles Adjust Flower Opening Time to Enhance the Seed Setting Rate Under High Temperature Stress

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4780-4798, August 2026.
ABSTRACT To safeguard global food security against rapid population growth and a warming world, the effective genetic improvement of cereals is imperative. Flower opening time (FOT) critically affects the seed setting rate. In this study, we identified a gene, EARLY‐MORNING FLOWERING 3 (EMF3), in which single‐nucleotide substitutions strongly modulate ...
Takuma Ishizaki, Yoichi Hashida, Hideyuki Hirabayashi, Kazuhiro Sasaki, Hiroki Tokunaga, Eliza Vie M. Simon‐Ada, Masataka Wakayama, Toshiyuki Takai, Hiroki Saito, Atsushi J. Nagano, Hitoshi Sakakibara, Mikiko Kojima, Yumiko Takebayashi, Sung‐Ryul Kim, Ryo Matsushima, Michael J. Thomson, Kazuhiko Sugimoto, Ken‐Ichiro Hibara, Tsutomu Ishimaru   +18 more
wiley   +1 more source

Um olhar atento aos fármacos, via CTS

Indagatio Didactica
No Ensino de Química busca-se construir atividades didáticas pedagógicas a partir de temas que possam contribuir de forma significativa na aprendizagem dos alunos.
Taís Conceição dos Santos, Valéria Pereira   +1 more
doaj   +1 more source

DNAJC12 Stabilizes Phenylalanine Hydroxylase and Facilitates Its Substrate‐Dependent Activation

The FASEB Journal, Volume 40, Issue 14, 31 July 2026.
Substrate‐induced activation of PAH by L‐Phe involves dimerization of its regulatory domains (RD), with L‐Phe binding in the dimeric RD interface. The J‐domain protein DNAJC12 binds this activated conformation, stabilizing PAH and delaying aggregation, while reducing the substrate concentration required for activation.
Mary Dayne S. Tai, Trond‐André Kråkenes, Gloria Gamiz‐Arco, Christer F. Didriksen, Juha P. Kallio, Marte I. Flydal, Fernando Moro, Aurora Martinez   +7 more
wiley   +1 more source

Integrating Deflection into Rule of Law and SDG Programming for UN Peace Operations

Journal of Multidisciplinary Studies in Human Rights and Science
EN | Abstract: This paper contends that deflection practices are relevant strategies to enhance Rule of Law and advance Sustainable Development Goals (SDGs) in United Nations (UN) peace operations.
Nixon M. Camilien
doaj   +1 more source

Dissection and Engineering of Modular Polyketide Synthase Extender Unit Specificity Motifs

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Motif‐level engineering of acyltransferase domains in polyketide synthases enables programable extender unit selectivity. Cooperative mutations and motif exchanges reprogram substrate preference, enabling the incorporation of non‐native extender units and expanding polyketide structural diversity, with gains in activity and product yield.
Sydney Welch, Gavin J. Williams
wiley   +1 more source