Results 141 to 150 of about 13,485,768 (280)

Actinomycin Analogs From Streptomyces polyantibioticus S4D258: Structural Elucidation and Antiproliferative Activity Against Triple‐Negative Breast Cancer

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Fifteen new actinomycin analogs, named actinomycins H1–H15, are identified from S. polyantibioticus S4D258. Actinomycins H7–H15 are truncated actinomycin analogs. Actinomycins H1–H6 and H9 exhibit significant antiproliferative activities against both MDA‐MB‐231 and 4T1 TNBC cells.
He Pang, Xiao‐Min Huang, Usama Ramadan Abdelmohsen, Li Shen, Jun Wu   +4 more
wiley   +1 more source

Mannosylxylarinols A and B, Two New 3,4‐Seco‐ergostane‐type Steroidal Saponins From the Fungus Xylaria necrophora SZSS1‐2‐2

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Two new 3,4‐seco‐ergostane saponins (1–2) and four known compounds were isolated from Xylaria necrophora. Structures were elucidated via spectroscopy, ECD, and computational NMR. Compound 5 selectively inhibited BV2 microglial cells (IC50 = 17.10 µM), while all compounds showed no antimicrobial activity against tested microorganisms. ABSTRACT Two new 3,
Qian Luo, Yu Yang, Rui Xu, Xue Zhao, Hui‐Fang Tan, Yu‐Ying Wei, Er‐Wei Li, Li‐Xia Chen, You‐Zhi Zhang, Chang‐Wei Li   +9 more
wiley   +1 more source

Challenges in glaucoma diagnosis in small optic discs: An OCT-based analysis. [PDF]

Medicine (Baltimore)
Yildiz S, Ugurlu Karadeniz S.
europepmc   +1 more source

Cytotoxic Dihydroagarofuran Sesquiterpenoids Isolated From the Roots of Tripterygium wilfordii

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ten undescribed dihydro‐β‐agarofuran derivatives were isolated from the roots of Tripterygium wilfordii. Their structures, including absolute configurations were elucidated by NMR, CD exciton chirality, ECD calculation, and single‐crystal x‐ray diffraction.
Ya‐Lin Hu, Yi‐Ping Xie, Jing‐Yi Huang, Chong Wang, Jia‐Li Huang, Wen‐Jie Chen, Zhen Li, Zuo‐Dong Qin   +7 more
wiley   +1 more source

Distinct enteric nervous system pattern in obstructed defecation syndrome and slow-transit constipation: a controlled digital pathology study. [PDF]

Int J Colorectal Dis
Bedau T, Mirzaie-Kuzehgarani A, Madukkakzhy J, Halbe L, Quaas A, Rudroff C.   +5 more
europepmc   +1 more source

UHPLC/MS‐MS Profiling, Antioxidant and Antimicrobial Properties of Atriplex halimus L. and Marrubium deserti De Noé Extracts: In Vitro and In Silico

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
This study investigates the phytochemical profile and biological potential of Atriplex halimus L. and Marrubium deserti De Noé extracts. Polyphenolic constituents are identified using UHPLC‐MS/MS analysis, complemented by TPC and TFC evaluations. Antioxidant activities are determined via DPPH, ABTS, and FRAP assays, while antimicrobial efficacy is ...
Nacira Siad, Chahrazed Hamia, Amar Djeridane, Mohamed Benalia, Reguia Mahfoudi, Hicham Bouakkaz, Mustafa Abdullah Yilmaz, Oguz Cakir, Abbas Tarhan, Mohamed Yousfi   +9 more
wiley   +1 more source

Paradoxical nutrient hyperabsorption despite diarrhea: Insights from jejunal transcriptomic reanalysis in Linghu's obesity-diarrhea syndrome. [PDF]

World J Gastrointest Pathophysiol
Niu XT, Wang XY, Linghu EQ.
europepmc   +1 more source

Bioactive Compounds and Cytotoxicity of Seed and Leaf Oils of Moringa oleifera

eFood, Volume 7, Issue 5, October 2026.
Among the practical applications of the oils described in this study, their use as an ingredient in food stands out, as well as the potential for developing bioactive materials for packaging, conferring antioxidant and antimicrobial properties. Seed and leaf oils from Moringa oleifera exhibit functional properties of industrial interest and bioactive ...
Emanuela de Lima Viana, Julia da Costa Santos, Ana Caroline de Medeiros Dantas, David Henrique Xavier Barbosa, Matheus de Freitas Fernandes Pedrosa, Pablo Felipe Ferreira Farias, Susana Margarida Gomes Moreira, Patrícia Prado Augusto, Patricia Santos Lopes, Ana Paula Barreto Gomes, Rui de Oliveira Macedo, Francisco Canindé de Sousa Júnior, Cristiane Fernandes de Assis   +12 more
wiley   +1 more source

Overcorrection of Hyponatremia: A Complicated Story. [PDF]

Electrolyte Blood Press
Kim GH.
europepmc   +1 more source

Conjugation of Coffee Phenolics With Milk Bioactive Peptides: Characterization of Coffee and Apple Phenolics and Evaluation of Polyphenol Oxidase as a Natural Biocatalyst

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Green coffee beans provided a chlorogenic acid (CQA)‐rich extract, while apple juice served as a natural source of polyphenol oxidase (PPO). The coffee phenolics were characterized by HPLC–MS and combined with milk bioactive peptides, BioZate1 and Glycomacropeptide, under alkaline and PPO‐mediated conditions.
Bandar N. Hamadneh, Entisar D. Mustafa, Mohamed E. Alkafafy, Ebtihal Khojah, Bassem N. Samra, Daniel Eutyche Mbadjoun Wapet, Mohamed Metwally Mahmoud, Waleed Z. Badawy, Mahmoud Khalil, Mohamed A. Salama, Mohamed Abdin, Mostafa Ali   +11 more
wiley   +1 more source