Results 161 to 170 of about 2,011,905 (264)

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Renal Function Preservation in Purely Off-Clamp Sutureless Robotic Partial Nephrectomy: Initial Experience and Technique. [PDF]

Diagnostics (Basel)
Franco A, Riolo S, Tema G, Guidotti A, Brassetti A, Anceschi U, Bove AM, D'Annunzio S, Ferriero M, Mastroianni R, Misuraca L, Guaglianone S, Tuderti G, Leonardo C, Cicione A, Licari LC, Bologna E, Flammia RS, Nacchia A, Trucchi A, Lombardo R, Franco G, Tubaro A, Simone G, De Nunzio C.   +24 more
europepmc   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

Predictors of renal function deterioration at one year after off-clamp non-renorrhaphy partial nephrectomy. [PDF]

PLoS One
Nakamura M, Kameyama S, Tsuru I, Izumi T, Ono A, Teshima T, Inoue Y, Amakawa R, Inatsu H, Yoshimatsu T, Kusakabe M, Morikawa T, Shiga Y.   +12 more
europepmc   +1 more source

Three-dimensional reconstruction facilitates off-clamp laparoscopic partial nephrectomy for stage cT1b renal tumors. [PDF]

Transl Cancer Res, 2020
Wu X, Shen C, Wu G, Jiang C, Fu Q, Liu D, Xue W.   +6 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Purely Off-Clamp Sutureless Robotic Partial Nephrectomy for Novice Robotic Surgeons: A Multi-Institutional Propensity Score-Matched Analysis. [PDF]

J Clin Med
De Nunzio C, Tema G, Brassetti A, Anceschi U, Bove AM, D'Annunzio S, Ferriero M, Mastroianni R, Misuraca L, Guaglianone S, Tuderti G, Leonardo C, Lombardo R, Cicione A, Franco A, Bologna E, Licari LC, Riolo S, Flammia RS, Nacchia A, Trucchi A, Franco G, Tubaro A, Simone G.   +23 more
europepmc   +1 more source

Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks

Advanced Science, EarlyView.
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley   +1 more source

Comparative Study Assessing Postoperative Renal Loss Using Two Different Partial Nephrectomy Techniques: Off-Clamp versus Standard On-Clamp Surgery. [PDF]

Curr Urol, 2020
Aquil S, Olvera-Posada D, Navaratnam R, Mikhail D, Levine MA, Luke PP, Sener A.   +6 more
europepmc   +1 more source