Results 111 to 120 of about 1,274,911 (296)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Low-Speed Airfoil Optimization for Improved Off-Design Performance

Aerospace
The advancement of computational capabilities has allowed for more efficient airfoil analysis and design. Consequently, it has become possible to expand the design space and explore new geometries and configurations.
Guilherme F. S. Pangas, Pedro V. Gamboa
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Creating spin-off : designing entrepreneurship conducive universities

, 2010
University spin-offs are companies founded to exploit university intellectual property. They serve to transform technological breakthroughs from university research, which would probably remain unexploited otherwise. Therefore, policy makers have become very interested in university spin-offs as a means for technology transfer and economic growth ...
openaire   +2 more sources

Model equation for simulating flows in multistage turbomachinery [PDF]

A steady, three-dimensional average-passage equation system is derived for use in simulating multistage turbomachinery flows. These equations describe a steady, viscous flow that is periodic from blade passage to blade passage.
Adamczyk, J. J.
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Two-dimensional viscous flow computations of hypersonic scramjet nozzle flowfields at design and off-design conditions [PDF]

The PARC2D code has been selected to analyze the flowfields of a representative hypersonic scramjet nozzle over a range of flight conditions from Mach 3 to 20.
Harloff, G. J., Lai, H. T., Nelson, E. S.   +2 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Design of Propellers for Motorsoarers [PDF]

A method was developed for the design of propellers of minimum induced loss matched to an arbitrary operating point characterized by disc loading (thrust or power), air density, shaft speed, flight speed, and number of blades.
Larrabee, E. E.
core   +1 more source