Results 121 to 130 of about 1,274,911 (296)
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Surface design with self-heating smart polymers for on–off switchable traps
Science and Technology of Advanced Materials, 2011 We have developed a novel self-heating, temperature-responsive chromatography system for the effective separation of biomolecules. Temperature-responsive poly(N-isopropylacrylamide-co-N-hydroxymethylacrylamide), poly(NIPAAm-co-HMAAm), was covalently ...
Prapatsorn Techawanitchai, Kazuya Yamamoto, Mitsuhiro Ebara and Takao Aoyagi
doaj
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Turbine modeling technique to generate off-design performance data for both single and multistage axial-flow turbines [PDF]
This technique is applicable to larger axial flow turbines which may or may not incorporate variable geometry in the first stage stator. A user specified option will also permit the calculation of design point cooling flow levels and the corresponding ...
Converse, G. L.
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Optimization of Heat Exchanger Design Parameters for Hydrocarbon Refrigerant Systems [PDF]
, 2004 Hydrocarbon refrigerants (HC's) are one alternative to hydrofluorocarbons (HFC???s) since they have zero ozone depletion potential and negligible global warming potential.
Bullard, C.W., Jain, S.
core
Unsteady aerodynamic effects in small-amplitude pitch oscillations of an airfoil
, 2018 High-fidelity wall-resolved large-eddy simulations (LES) are utilized to investigate the flow-physics of small-amplitude pitch oscillations of an airfoil at Re = 100,000.
Hanifi, Ardeshir +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Supersonic through-flow fan design [PDF]
The NASA Lewis Research Center has embarked on a program to experimentally prove the concept of a supersonic through-flow fan which is to maintain supersonic velocities throughout the compression system with only weak shock-wave flow losses. The detailed
Moore, Royce D. +3 more
core +1 more source