Results 111 to 120 of about 3,018,484 (379)
Learning a Policy for Opportunistic Active Learning
, 2018 Active learning identifies data points to label that are expected to be the most useful in improving a supervised model. Opportunistic active learning incorporates active learning into interactive tasks that constrain possible queries during interactions.
Mooney, Raymond J. +2 more
core +1 more source
The Benefit and Risk of Misoprostol Use: in Obstetrics and Gynecology [PDF]
, 2015 Misoprostol is licensed to treat gastric ulcers but now it is widely used for a variety of indications in osbtetrics and gynecology. This is called ‘off-label' use. Misoprostol is cheap, stable at room temperature and easily to access it.
Desrini, S. (Sufi)
core +2 more sources
Gabapentin for Off-Label Use: Evidence-Based or Cause for Concern?
Substance abuse : research and treatment, 2018 Gabapentin is widely used in the United States for a number of off-label indications, often as an alternative to opioid therapy. Increasing evidence has emerged suggesting that gabapentin may not be as benign as once thought and may be associated with ...
Alyssa M. Peckham +3 more
semanticscholar +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Dealing with Excessive Off-label Drug Use: Liability vs. Patent Prolongation [PDF]
The US and the EU recently introduced regulation to curb the extent of risky off-label drug use. It offers manufacturers a prolongation of patent protection or exclusivity if they invest in pediatric clinical tests.
Anja Olbrich, Stefan Felder
core
Probabilistic Label Relation Graphs with Ising Models
, 2015 We consider classification problems in which the label space has structure. A common example is hierarchical label spaces, corresponding to the case where one label subsumes another (e.g., animal subsumes dog).
Deng, Jia +3 more
core +1 more source
Sailing the straits of approval: The nature of FDA approval and its implications for surgeons [PDF]
, 2007 Products approved by the US Food and Drug Administration (FDA) for one use are often put to other uses. This practice, known colloquially as off-label usage, is neither illegal nor unethical.
Reiter, David, MD
core +2 more sources
Chinese Journal of Contemporary Neurology and Neurosurgery, 2012 Objective To investigate current status and safety about off⁃label use of levetiracetam, topiramate, oxcarbazepine, lamotrigine among pediatric patients in Sichuan area, so as to provide baseline data for formulating guidelines of off ⁃ label drug use ...
Qian⁃yun CAI +7 more
doaj
[Off-label use of alitretinoin].
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2013 Oral alitretinoin (9-cis retinoic acid) is an endogenous retinoid related to vitamin A. Studies have shown that oral alitretinoin is effective and well-tolerated in the treatment of severe chronic hand eczema, so that it is approved for this indication. This review summarizes new studies and clinical experience on the off-label use of alitretinoin.
Onder, M. +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source