Results 161 to 170 of about 3,018,484 (379)
Off-label use of a medium-high molecular weight, isotonic and sterile hyaluronic acid in aesthetic medicine. Cases report [PDF]
, 2018 F Svolacchia, L Svolacchia
openalex +1 more source
Off-label use of antipsychotics: rethinking "off-label".
Psychiatria Danubina, 2008 Antipsychotics are currently registered for the use in psychosis, mania and agitation. They have although been in common practice used for a wide range of psychiatric disorders even in the era of first generation antipsychotics. Such a use is termed "off-label". There are several drawbacks in off-label antipsychotics' prescribing among them legislative
openaire +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Challenges on off label medicine use
Revista Paulista de Pediatria, 2016 Marisa Lima Carvalho
doaj +1 more source
CEUS Guidelines: Evidence Based Medicine or off Label Use? [PDF]
, 2017 Christian Nolsøe
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Off-Label Use of Botulinum Toxin in Dermatology—Current State of the Art [PDF]
, 2022 Miłosz Lewandowski +2 more
openalex +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
A dramatic case of Behçet disease successfully treated with infliximab [PDF]
, 2013 Behçet disease is a chronic relapsing systemic disease with possible life-threatening presentations. Management of this disease can be challenging and reports of the off-label use of anti-TNFα agents for the treatment of severe manifestations are ...
Alves, R. +3 more
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