Results 11 to 20 of about 3,028,209 (373)

Off-label use of intravenous thrombolysis for acute ischemic stroke: a critical appraisal of randomized and real-world evidence

open access: yesTherapeutic Advances in Neurological Disorders, 2021
Intravenous thrombolysis (IVT) represents the only systemic reperfusion therapy able to reverse neurological deficit in patients with acute ischemic stroke (AIS).
G. Tsivgoulis   +13 more
semanticscholar   +1 more source

Management guideline for the off-label use of medicine in China (2021)

open access: yesExpert Review of Clinical Pharmacology, 2022
Background Off-label drug use embodies a thorough clinical diagnosis and evaluation of treatment needs and should not be confused with unreasonable drug use, but it also faces potential risks with drug safety and legal issues. Research design and methods
W. Zuo   +18 more
semanticscholar   +1 more source

Off-label antineoplastic drugs. An effectiveness and safety study [PDF]

open access: yesFarmacia Hospitalaria, 2017
Objective: The use of antineoplastic medicines in special situations is common in clinical practice; it is strongly regulated and there is little information on its outcomes.
Cristina Arroyo Álvarez   +5 more
doaj   +1 more source

Off-Label Drug Use in Oncology

open access: yesКреативная хирургия и онкология, 2022
The off-label use of medicines is a routine clinical practice of oncology, especially in malignant-tumour patients with no treatment alternatives left when registered-drug options have been exhausted or standard therapies reveal contraindications.
E. V. Karabina   +2 more
doaj   +1 more source

Off-label antibiotic use in a specialized children care hospital in Punjab, Pakistan: Findings and implications

open access: yesJournal of Infection in Developing Countries, 2020
Introduction: Most of the antibiotics currently used in pediatrics are either unlicensed or being prescribed outside the specifications of product label (off-label prescribing).
Muhammad Hafeez   +6 more
doaj   +1 more source

Use of antipsychotics in Denmark 1997–2018: a nation-wide drug utilisation study with focus on off-label use and associated diagnoses

open access: yesEpidemiology and Psychiatric Sciences, 2021
Aims Antipsychotics are primarily labelled for the treatment of severe mental illness and have documented clinical utility in certain neurological disorders or palliative care.
M. Højlund   +4 more
semanticscholar   +1 more source

Off-label Use of Direct Oral Anticoagulants Compared With Warfarin for Left Ventricular Thrombi.

open access: yesJAMA cardiology, 2020
Importance Left ventricular (LV) thrombi can arise in patients with ischemic and nonischemic cardiomyopathies. Anticoagulation is thought to reduce the risk of stroke or systemic embolism (SSE), but there are no high-quality data on the effectiveness of ...
A. Robinson   +13 more
semanticscholar   +1 more source

Recommendations on off‐label use of intravenous azithromycin in children

open access: yesInternational journal of clinical practice, 2021
Intravenous azithromycin (AZM) has been widely used in children worldwide, but there still remains much concern regarding its off‐label use, which urgently needs to be regulated.
Pengxiang Zhou   +7 more
semanticscholar   +1 more source

Off-Label Use [PDF]

open access: yesBulletin des Médecins Suisses, 2014
Off-label use of drugs and other agents can be very anxiety-producing for doctors because of concerns related to potential malpractice suits. Until quite recently, once an agent was approved it could only be marketed/promoted by the pharmaceutical company for the use or disease indication (intended indication) and in the manner described on the ...
  +4 more sources

Off-label prescribing of antipsychotics: prescribing practices and clinical experiences of Finnish physicians

open access: yesEuropean Psychiatry, 2022
Introduction Off-label use of antipsychotics has increased in many countries. In adult populations antipsychotics off-label prescriptions varied from 40 to 75% of all AP users.
N. Rautio   +11 more
doaj   +1 more source

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