Results 11 to 20 of about 3,018,484 (379)

Use of antipsychotics in Denmark 1997–2018: a nation-wide drug utilisation study with focus on off-label use and associated diagnoses

open access: yesEpidemiology and Psychiatric Sciences, 2021
Aims Antipsychotics are primarily labelled for the treatment of severe mental illness and have documented clinical utility in certain neurological disorders or palliative care.
M. Højlund   +4 more
semanticscholar   +1 more source

Off-label Use of Direct Oral Anticoagulants Compared With Warfarin for Left Ventricular Thrombi.

open access: yesJAMA cardiology, 2020
Importance Left ventricular (LV) thrombi can arise in patients with ischemic and nonischemic cardiomyopathies. Anticoagulation is thought to reduce the risk of stroke or systemic embolism (SSE), but there are no high-quality data on the effectiveness of ...
A. Robinson   +13 more
semanticscholar   +1 more source

Off-label use of anti-IL-1 drugs in rheumatic diseases

open access: yesInternational Journal of Immunopathology and Pharmacology, 2021
Interleukin-1 (IL-1) plays a key role in the pathogenesis of different rheumatic diseases. There are now several agents available on the market capable of blocking IL-1.
S. Stefania   +4 more
semanticscholar   +1 more source

Off-Label Use [PDF]

open access: yesBulletin des Médecins Suisses, 2014
Off-label use of drugs and other agents can be very anxiety-producing for doctors because of concerns related to potential malpractice suits. Until quite recently, once an agent was approved it could only be marketed/promoted by the pharmaceutical company for the use or disease indication (intended indication) and in the manner described on the ...
  +4 more sources

Off-label prescribing of antipsychotics: prescribing practices and clinical experiences of Finnish physicians

open access: yesEuropean Psychiatry, 2022
Introduction Off-label use of antipsychotics has increased in many countries. In adult populations antipsychotics off-label prescriptions varied from 40 to 75% of all AP users.
N. Rautio   +11 more
doaj   +1 more source

Pediatric Off‐Label Use of Covid‐19 Vaccines: Ethical and Legal Considerations

open access: yesThe Hastings center report, 2021
When the U.S. Food and Drug Administration fully approved the Pfizer‐BioNTech Covid‐19 vaccine for people sixteen and older, questions arose. Parents, pediatricians, and the media wondered whether Covid‐19 vaccines could be used off‐label—and whether ...
Elizabeth Lanphier, Shannon Fyfe
semanticscholar   +1 more source

The peculiarities of off-label use of drugs in pediatrics

open access: yesZaporožskij Medicinskij Žurnal, 2020
Prescribing drugs is not an easy task for pediatricians since the range of choice of drugs in pediatrics is 2/3 less than in adult patients. The aim of this work is to analyze the literature data on the experience of using off-label drugs in ...
S. M. Drohovoz   +5 more
doaj   +1 more source

EFORT recommendations for off-label use, mix & match and mismatch in hip and knee arthroplasty

open access: yesEFORT Open Reviews, 2021
Off-label use is frequently practiced in primary and revision arthroplasty, as there may be indications for the application of implants for purposes outside the one the manufacturers intended.
K. Tucker   +7 more
semanticscholar   +1 more source

Efficacy of Off-Label Use of Anticancer Drugs in Oncology

open access: yesКреативная хирургия и онкология, 2023
The off-label use of anticancer drugs is widespread in modern oncology. The potential advantages of such prescriptions are associated with exceeding the expected clinical benefi ts over the risks of complications.
E. V. Karabina   +2 more
doaj   +1 more source

Recommendations on off‐label use of intravenous azithromycin in children

open access: yesInternational journal of clinical practice, 2021
Intravenous azithromycin (AZM) has been widely used in children worldwide, but there still remains much concern regarding its off‐label use, which urgently needs to be regulated.
Pengxiang Zhou   +7 more
semanticscholar   +1 more source

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