Results 21 to 30 of about 3,028,209 (373)

EFORT recommendations for off-label use, mix & match and mismatch in hip and knee arthroplasty

EFORT Open Reviews, 2021
Off-label use is frequently practiced in primary and revision arthroplasty, as there may be indications for the application of implants for purposes outside the one the manufacturers intended.
K. Tucker, K. Günther, P. Kjaersgaard-Andersen, J. Lützner, J. Kretzer, R. Nelissen, T. Lange, L. Zagra   +7 more
semanticscholar   +1 more source

The peculiarities of off-label use of drugs in pediatrics

Zaporožskij Medicinskij Žurnal, 2020
Prescribing drugs is not an easy task for pediatricians since the range of choice of drugs in pediatrics is 2/3 less than in adult patients. The aim of this work is to analyze the literature data on the experience of using off-label drugs in ...
S. M. Drohovoz , Ya. O. Butko, L. B. Іvantsyk, C. H. Shchokina, H. V. Bielik , V. D. Lukianchuk   +5 more
doaj   +1 more source

Pediatric Off‐Label Use of Covid‐19 Vaccines: Ethical and Legal Considerations

The Hastings center report, 2021
When the U.S. Food and Drug Administration fully approved the Pfizer‐BioNTech Covid‐19 vaccine for people sixteen and older, questions arose. Parents, pediatricians, and the media wondered whether Covid‐19 vaccines could be used off‐label—and whether ...
Elizabeth Lanphier, Shannon Fyfe
semanticscholar   +1 more source

Use of off-label drugs and the prevalence of adverse reaction to drugs in the adult intensive care unit of a Brazilian public hospital

Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde, 2023
Objective: To Identify the occurrence of adverse reactions to medications (ADR) in patients using off-label prescriptions admitted in an adult intensive care unit (ICU).
Lívia P. MOREIRA, Marjorie M. GUEDES, Eunice B. PERRAUD, Arnaldo A. PEIXOTO-JUNIOR, Eudiana V. FRANCELINO, Marta F. FONTELES   +5 more
doaj   +1 more source

Off-label use of anti-IL-1 drugs in rheumatic diseases

International Journal of Immunopathology and Pharmacology, 2021
Interleukin-1 (IL-1) plays a key role in the pathogenesis of different rheumatic diseases. There are now several agents available on the market capable of blocking IL-1.
S. Stefania, R. Colia, Rotondo Cinzia, A. Corrado, F. Cantatore   +4 more
semanticscholar   +1 more source

Association of Supporting Trial Evidence and Reimbursement for Off-Label Use of Cancer Drugs

JAMA Network Open, 2021
Key Points Question Is evidence from randomized clinical trials associated with the reimbursement decisions that determine access to off-label use of cancer drugs in Switzerland? Findings In this cross-sectional study including 3046 patients with cancer,
A. Herbrand, A. Schmitt, M. Briel, Hannah Ewald, M. Goldkuhle, S. Diem, Anouk Hoogkamer, M. Joerger, G. Moffa, U. Novak, L. Hemkens, B. Kasenda   +11 more
semanticscholar   +1 more source

Off-label use of rilpivirine in combination with emtricitabine and tenofovir in HIV-1-infected pediatric patients

Medicine, 2016
To assess the safety and efficacy of rilpivirine in combination with emtricitabine and tenofovir (RPV/FTC/TDF) as a once-daily single-tablet regimen (STR) in HIV-1-infected children and adolescents we performed a multicenter case series study of HIV-1 ...
Lola Falcón-Neyra, C. Palladino, M. N. Navarro Gómez, P. Soler-Palacín, M. González-Tomé, S. J. de Ory, M. Frick, C. Fortuny, A. Noguera-Julian, Elena Bermúdez Moreno, J. Santos, P. Olbrich, L. López-Cortés, V. Briz, O. Neth   +14 more
semanticscholar   +1 more source

Trends in off-label use of antipsychotic medications among Texas Medicaid children and adolescents from 2013 to 2016

Journal of Managed Care & Specialty Pharmacy, 2021
BACKGROUND: Antipsychotics are frequently prescribed for off-label indications in the pediatric population. However, little is known regarding this issue in Texas Medicaid.
Shuang Chen, J. Barner, Eun Cho
semanticscholar   +1 more source

Evaluation of Knowledge, Attitudes and Experience of off-label Drug Prescribing Practice among Physicians in Baghdad City Hospitals

Iraqi Journal of Pharmaceutical Sciences, 2019
The present study aims to assess the knowledge, attitude, and experience of off-label prescribing practice among physicians in Baghdad city hospitals. This cross-sectional study was performed through the period from November 1st 2018 to March 2019 at 17 ...
Aysha M. Shanshal, Ahmed H. Ataimish
doaj   +1 more source

Off-label Use of Antibiotics in Pediatrics [PDF]

Pediatric Infectious Disease, 2022
Usage of antibiotics off-label, in neonates and children, is an important public health issue. An overwhelming number of antibiotics are marketed and prescribed without clear labeling for use in pediatrics.
Jeeson C Unni
doaj   +1 more source