Results 51 to 60 of about 3,028,209 (373)
An Evaluation of the Effectiveness of Risk Minimization Measures for Tigecycline in the European Union [PDF]
, 2017 Background: Risk minimization measures (RMM) were implemented from February 2011 in the European Union to address risks of superinfection, off-label use and lack of efficacy associated with tigecycline.
Baillon Plot, Nathalie +10 more
core +1 more source
An Off-Label Use of Parental Rights? The Unanticipated Doctrinal Antidote for Professor Mnookin’s Diagnosis [PDF]
, 2014 In the intersection of technology, curriculum and intentions, a specific issue of interest is found in the gap between teachers’ intentions and implementations of curriculum.
Buss, Emily
core +3 more sources
International Journal of Pediatrics, 2014 Background. In the absence of standard pediatric prescribing information, clinicians often use medicines in an off-label way. Many studies have been published across the globe reporting different rates of off-label use.
Mohd Masnoon Saiyed +2 more
doaj +1 more source
Evidence and Extrapolation: Mechanisms for Regulating Off-Label Uses of Drugs and Devices [PDF]
, 2014 A recurring, foundational issue for evidence-based regulation is deciding whether to extend governmental approval from an existing use with sufficient current evidence of safety and efficacy to a novel use for which such evidence is currently lacking ...
Abbott, Ryan, Ayres, Ian
core +3 more sources
COVID-19 and off label use of drugs: an ethical viewpoint
DARU Journal of Pharmaceutical Sciences, 2020 The COVID-19 outbreak is rapidly spread over the world and kills infected patients. There is no proven medication for its treatment, so, all of the medications used for treatment are considered to be off-label.
Amirahmad Shojaei, P. Salari
semanticscholar +1 more source
Observational study on off-label use of tocilizumab in patients with severe COVID-19
European Journal of Hospital Pharmacy: Science and Practice, 2020 Background In December 2019 a novel coronavirus designated SARS-CoV-2 was identified, and the disease COVID-19 has caused many deaths. SARS-CoV-2 infection has been associated with the development of cytokine storm (including interleukin 6 (IL-6)), which
Laetitia Albertini +9 more
semanticscholar +1 more source
Off-label prescription of drugs at hospital [PDF]
Farmacia Hospitalaria, 2016 Objectives: To develop a procedure for management of off-label medications, and to analyze the treatments, indications, and hospital units which will request them more frequently, as well as which variables will have an impact on the authorization ...
Vicente Arocas Casañ +6 more
doaj +1 more source
Automated Detection of Systematic Off-label Drug Use in Free Text of Electronic Medical Records. [PDF]
, 2013 Off-label use of a drug occurs when it is used in a manner that deviates from its FDA label. Studies estimate that 21% of prescriptions are off-label, with only 27% of those uses supported by evidence of safety and efficacy.
Jung, Kenneth +2 more
core +2 more sources
Available evidence and outcome of off-label use of rituximab in clinical practice [PDF]
, 2013 Purpose: To analyze the therapeutic indications for off-label use of rituximab, the available evidence for its use, the outcomes, and the cost. Methods: This was a retrospective analysis of patients treated with rituximab for off-label indications from ...
A. Agustí +34 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small +3 more
wiley +1 more source