Results 71 to 80 of about 3,028,209 (373)

Clinical outcomes of endurant II stent-graft for infrarenal aortic aneurysm repair: Comparison of on-label versus off-label use [PDF]

, 2016
PURPOSE We aimed to compare the outcomes of the Endurant II (Medtronic) stent-graft used under instructions for use versus off-label in high-risk patients considered unfit for conventional surgery.
Badalamenti, G., BAJARDI, Guido, Bruno, S., Corte, G., Dinoto, E., PECORARO, Felice   +5 more
core   +2 more sources

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Analysis of off-label drug use and its influencing factors in pediatric patients undergoing otolaryngology, head, and neck surgery

Frontiers in Pharmacology
BackgroundTo date, there are limited data regarding off-label drug use in pediatric patients undergoing otolaryngology, head, and neck surgery. This study aimed to investigate the prevalence and patterns of off-label drug use among outpatients under 18 ...
Zichao Ji, Xin Wang, Jiawei Wang
doaj   +1 more source

Use of unlicensed and off-label drugs in neonates in a Brazilian university hospital

Brazilian Journal of Pharmaceutical Sciences, 2018
This study was designed to investigate the use of off-label and unlicensed drugs in a Neonatal Care Unit (NCU) and to compare the frequency of use of off-label drugs according to the drug regulatory agencies in Brazil (Agência Nacional de Vigilância ...
Adriana Cristina de Souza Gonçalves, Adriano Max Moreira Reis, Ana Carolina Gusmão Marçal, Maria Cândida Ferrarez Bouzada   +3 more
doaj   +1 more source

Off-label use of misoprostol in gynaecology [PDF]

, 2015
Clinical use of drugs is approved for specified clinical indication, route of administration, dose and population group. Off-label prescribing of a registered medicine occurs outside of these parameters and may be justified by pharmacology and physiology,
Agatonovic-Kustrn, S., Turner, J. V., Ward, H. R. G.   +2 more
core  

Off-label use of rituximab for systemic lupus erythematosus in Europe [PDF]

, 2018
K
Boumpas, Dimitrios, Bultink, Irene, Callejas Rubio, Jose Luis, Caminal-Montero, Luis, Castro, Antoni, Colodro Ruiz, Agustín, Doria, Andrea, Dörner, Thomas, Gonzalez-Echavarri, Cristina, Gremese, Elisa, Houssiau, Frederic A, Huizinga, Tom, Inanç, Murat, Isenberg, David, Iuliano, Annamaria, Jacobsen, Søren, Jimenéz-Alonso, Juan, Kovács, Lászlo, Mariette, Xavier, Mosca, Marta, Nived, Ola, Oristrell, Joaquim, Ramos-Casals, Manuel, Rascón, Javier, Ruiz-Irastorza, Guillermo, Rydén-Aulin, Monica, Salvador Cervelló, Gonzalo, Sebastiani, Gian Domenico, Squatrito, Danilo, Szücs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus), Szücs, Gabriella, Sáez-Comet, Luis, van Vollenhoven, Ronald, Voskuyl, Alexandre   +33 more
core   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Hypoglycemia associated with off-label sitagliptin use

International Medical Case Reports Journal, 2008
Heather P Whitley1,2, Kristi Kelley11Department of Pharmacy Practice, Auburn University Harrison School of Pharmacy, Auburn, AL, USA; 2Department of Community and Rural Medicine, University of Alabama School of Medicine, Tuscaloosa, AL, USAPurpose: To ...
Heather P Whitley, Kristi Kelley
doaj  

\u3ci\u3eUnited States v. Caronia\u3c/i\u3e: Off-Label Drug Promotion and First Amendment Balancing [PDF]

, 2018
Off-label drug promotion is commonplace in the United States, but it is not without its dangers. While the Food, Drug, and Cosmetic Act does not explicitly ban off-label promotion, the Food & Drug Administration (FDA)— in order to protect consumers from ...
Rabinowitz, Daniel P.
core   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source