Results 81 to 90 of about 3,028,209 (373)

Fentanyl self-testing outside supervised injection settings to prevent opioid overdose: Do we know enough to promote it? [PDF]

, 2018
Since 2013, North America has experienced a sharp increase in unintentional fatal overdoses: fentanyl, and its analogues, are believed to be primarily responsible.
Australian Injecting & Illicit Drug Users League, Catherine R. McGowan, Centers for Disease Control and Prevention, Ciccarone, Ciccarone, Ciccarone, Clark, Compton, Cressman, Daniulaityte, European Monitoring Centre for Drugs and Drug Addiction, Fairbairn, Frank, Friedman, Gladden, Harris, Human Rights Watch, Johns Hopkins Bloomberg School of Public Health, Jozaghi, Lucy Platt, Lysyshyn, Magdalena Harris, Marshall, Massey, McGowan, Messac, Mounteney, Murray, Neira-Leon, O'Donnell, Quest, Rhodes, Rhodes, Rhodes, Rhodes, Schneider, Seth, Shaheen, Socias, Stewart, The Vancouver Sun, Tim Rhodes, United Nations Office on Drugs and Crime, United States Drug Enforcement Administration, United States Drug Enforcement Administration, Vivian Hope, Winstock   +46 more
core   +2 more sources

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Off-label medication use in pediatrics and associated factors at public hospitals in east Gojjam zone, Ethiopia

SAGE Open Medicine, 2022
Objective: Due to a lack of appropriate pediatric preparations, health providers frequently use adult formulations in an off-label manner. This study aimed to assess pediatric off-label medication use patterns and associated factors in East Gojjam ...
Anteneh Belayneh, Eyasu Abatneh, Dehinnet Abebe, Melese Getachew, Bekalu Kebede, Bekalu Dessie   +5 more
doaj   +1 more source

Antipsychotics in off-label use: prescription practices, benefits and risks Results from APSY Oulu study

European Psychiatry, 2023
Introduction Use of antipsychotics (APs) has increased worldwide during last decades. Main reason for this is off-label use, and especially the use of quetiapine for insomnia and anxiety.
E. Jääskeläinen
doaj   +1 more source

FDA’s Position on Off-Label Use and Promotion of Drugs and Devices and Recent Enforcement Efforts by the Department of Justice [PDF]

, 2012
Off-label drug or medical device “use” is the practice of prescribing drugs or medical devices to patients for a purpose not included on the federally approved label.
Foster, Suzanne
core  

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

The use of the myocardial cytoprotector trimetazidine in a patient with angina as an example of off-label use

Кардиоваскулярная терапия и профилактика, 2019
The clinical case of the successful use of the myocardial cytoprotector trimetazidine as a universal anti-ischemic agent in a patient with hemodynamic angina due to myocardial bridging is described.
O. V. Tsygankova, L. D. Latyntseva, T. I. Batluk, D. Yu. Platonov, N. M. Akhmedzhanov   +4 more
doaj   +1 more source

Exhausted or Unlicensed: Can Field-of-Use Restrictions in Biotech License Agreements Still Prevent Off-Label Use Promotion After Quanta Computer? [PDF]

, 2010
[Excerpt] “In the biotechnology (biotech) industry, companies must be increasingly aware of their intellectual property and how their licensing strategies can impact their rights.
Wicks, Kristal M.
core   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

Outstanding questions concerning the regulation of enhancement devices [PDF]

, 2014
The authors (Maslen et al., 2014) propose to regulate cognitive enhancement devices (CEDs) as medical devices. Extending medical device regulations to CEDs raises some important questions that need to be adequately addressed before it makes sense to ...
De Ridder, Dirk, Focquaert, Farah, Vanneste, Sven   +2 more
core   +3 more sources