Results 131 to 140 of about 172,532 (307)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Comparison of the Plasma Metabolome Profiles Between the Internal Thoracic Artery and Ascending Aorta in Patients Undergoing Coronary Artery Bypass Graft Surgery Using Gas Chromatography Time-of-Flight Mass Spectrometry. [PDF]

, 2019
BackgroundThe left internal thoracic artery (LITA) has been used as the first conduit of choice in coronary artery bypass grafting (CABG) because of excellent long-term patency and outcomes.
Cho, Joo Youn, Hwang, Ho Young, Jang, Cholsoon, Jang, In Jin, Kim, Andrew HyoungJin, Kim, Ji Seong, Kim, Ki Bong   +6 more
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Bypass grafting operations using conventional technique with off-pump coronary artery bypass grafting in two identical groups conducted at the Penang Hospital (1999-2000) [PDF]

, 2001
This is a prospective study conducted at the Department of Cardiothoracic Surgery, Penang Hospital, Penang, with a total of one hundred patients were studied over a period of one year between January 1999 to January 2000. Fifty patients who had undergone
Kasinathan, Vasantha
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

On Pump versus Off Pump Coronary Artery Bypass Surgery in Patients Over Seventy Years Old with Triple Vessels Disease and Severe Left Ventricle Dysfunction: Focus on Early Clinical Outcomes

Acta Medica Iranica, 2013
Cardiovascular disease is the leading reason of morbidity in older people. Coronary artery bypass graft (CABG) surgery is the most common type of operations in world.
Seyed Jalil Mirhosseini, Seyed Khalil Forouzannia, Sadegh Ali-Hassan-Sayegh, Mehdi Hadad-Zadeh, Mohammad Hassan Abdollahi, Hossein Moshtaghiom, Habiballah Hosseini   +6 more
doaj   +2 more sources

Direct Access Valve Replacement (DAVR) — are we entering a new era in cardiac surgery? [PDF]

, 2017
Objective: This study validates the off-pump antegrade trans-ventricular route for ultrasound-guided direct access aortic valve replacement. Direct access aortic valve replacement using a transthoracic and valved stent-based approach offers numerous ...
Huber, Christoph H., von Segesser, Ludwig K.   +1 more
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Outcomes of off-pump complete bilateral internal thoracic artery grafting in patients with multivessel coronary artery disease

Российский кардиологический журнал
Aim. To analyze inhospital and mid-term outcomes of offand on-pump complete bilateral internal thoracic artery (BITA) grafting in patients with multivessel coronary artery disease (CAD).Material and methods.
A. G. Muradov, Yu. I. Grinshteyn, V. A. Sakovich   +2 more
doaj   +1 more source